Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | MAPT | P10636 | 6/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.56 |
| ▸ | AURKA | O14965 | 1/20 | 0.56 |
| ▸ | JAK2 | O60674 | 1/20 | 0.56 |
| ▸ | ABL1 | P00519 | 1/20 | 0.56 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.56 |
| ▸ | CSF1R | P07333 | 1/20 | 0.56 |
| ▸ | RET | P07949 | 1/20 | 0.56 |
| ▸ | MET | P08581 | 1/20 | 0.56 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL218018 | 0.90 | MAPT (0.78) | ALDH1A1MAPTMAPK1L3MBTL1CYP3A4 | |
| Ammonia Solution, Strong SCHEMBL29558993 | 0.88 | MAPT (0.75) | ALDH1A1MAPTMAPK1L3MBTL1CYP3A4 | |
| Hydrogen Sulfide SCHEMBL28326954 | 0.88 | MAPT (0.75) | ALDH1A1MAPTMAPK1L3MBTL1CYP3A4 | |
| Phosphine SCHEMBL30201038 | 0.88 | MAPT (0.75) | ALDH1A1MAPTMAPK1L3MBTL1CYP3A4 | |
| 4-Nitroaniline SCHEMBL10394016 | 0.87 | ALDH1A1 (0.53) | ALDH1A1MAPTMAPK1L3MBTL1CYP3A4 | |
| Iodide SCHEMBL10484653 | 0.86 | MAPT (0.72) | ALDH1A1MAPTMAPK1L3MBTL1CYP3A4 | |
| Acetonitrile SCHEMBL8872742 | 0.85 | MAPT (0.66) | ALDH1A1MAPTMAPK1L3MBTL1CYP3A4 | |
| SCHEMBL8908011 | 0.84 | ALDH1A1 (0.75) | ALDH1A1MAPTMAPK1L3MBTL1CYP3A4 | |
| SCHEMBL19190713 | 0.84 | ALDH1A1 (0.75) | ALDH1A1MAPTMAPK1L3MBTL1CYP3A4 | |
| SCHEMBL9948773 | 0.84 | MAPT (0.70) | ALDH1A1MAPTMAPK1L3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1366018-A1 | OMEGA-AMINOALKYLAMIDES OF R-2-ARYL-PROPIONIC ACIDS AS INHIBITORS OF THE CHEMOTAXIS OF POLYMORPHONUCLEATE AND MONONUCLEATE CELLS | Dompé S.P.A. (IT) | 2003-12-03 | — | — | EP | disclosed |
| WO-2002068377-A1 | OMEGA-AMINOALKYLAMIDES OF R-2-ARYL-PROPIONIC ACIDS AS INHIBITORS OF THE CHEMOTAXIS OF POLYMORPHONUCLEATE AND MONONUCLEATE CELLS | Dompé S.p.A. (IT) | 2002-09-06 | — | — | WO | disclosed |