Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 18/20 | 0.70 |
| ▸ | RXRB | P28702 | 10/20 | 0.59 |
| ▸ | RXRG | P48443 | 9/20 | 0.59 |
| ▸ | RARB | P10826 | 6/20 | 0.53 |
| ▸ | RARG | P13631 | 6/20 | 0.53 |
| ▸ | RARA | P10276 | 5/20 | 0.53 |
| ▸ | HNF4A | P41235 | 1/20 | 0.50 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9208986 | 0.83 | RXRA (0.78) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL1269026 | 0.83 | RXRA (1.00) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL22163720 | 0.81 | RXRA (0.50) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL6916396 | 0.81 | RXRA (1.00) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL6915230 | 0.81 | RXRA (0.67) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL7716684 | 0.80 | RXRA (0.67) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL6916398 | 0.79 | RARB (0.68) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL14017859 | 0.79 | RARB (0.68) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL6913706 | 0.79 | RXRA (0.74) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL7158137 | 0.79 | RXRA (0.68) | RXRARXRBRXRGRARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6545049-B1 | E.g., (2E, 4E, 6E)-7-(3,5-diisopropyl-2-n-heptyloxyphenyl)-3-methylocta-2,4,6-trienoic acid, esters or amides thereof | LIGAND PHARMACEUTICALS INCORPORATED | 2003-04-08 | — | — | US | disclosed |