Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6369321 | 1.00 | BRD4 (0.30) | BRD4 | |
| SCHEMBL6301635 | 1.00 | BRD4 (0.30) | BRD4 | |
| Hydrochloric Acid SCHEMBL6364352 | 0.98 | — | — | |
| SCHEMBL6309261 | 0.77 | PIK3CD (0.40) | — | |
| SCHEMBL6846167 | 0.75 | CYP19A1 (0.32) | — | |
| SCHEMBL7031086 | 0.75 | CYP19A1 (0.32) | — | |
| SCHEMBL23182954 | 0.68 | MAOA (0.35) | — | |
| SCHEMBL23683787 | 0.66 | SETD7 (0.32) | — | |
| SCHEMBL6301763 | 0.66 | GAA (0.38) | BRD4 | |
| SCHEMBL21350070 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1353910-A2 | LACTAM COMPOUND | ELI LILLY AND COMPANY (US) | 2003-10-22 | — | — | EP | disclosed |
| EP-1345955-A2 | LACTAM DIPEPTIDE AND ITS USE IN INHIBITING BETA-AMYLOID PEPTIDE RELEASE | ELI LILLY AND COMPANY (US) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002040451-A2 | LACTAM COMPOUND | ELI LILLY AND COMPANY (US) | 2002-05-23 | — | — | WO | disclosed |
| WO-2002040508-A2 | LACTAM DIPEPTIDE AND ITS USE IN INHIBITING BETA-AMYLOID PEPTIDE RELEASE | ELI LILLY AND COMPANY (US) | 2002-05-23 | — | — | WO | disclosed |