SCHEMBL7158482

SCHEMBL7158482

O=C(C1=CCCCC1)C1C=CCCC1

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HDAC2 Q92769 4/20 0.43
HDAC4 P56524 2/20 0.43
HDAC8 Q9BY41 2/20 0.43
HDAC6 Q9UBN7 2/20 0.43
HDAC1 Q13547 3/20 0.37
HDAC3 O15379 2/20 0.37
HDAC7 Q8WUI4 1/20 0.37
HDAC5 Q9UQL6 1/20 0.37
CCR2 P41597 1/20 0.37
CTSK P43235 1/20 0.36
HSD11B1 P28845 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12960759 0.77
SCHEMBL9061469 0.75 HDAC2 (0.46) HDAC2HDAC4HDAC8HDAC6HDAC1
SCHEMBL6268542 0.74 HDAC2 (0.52) HDAC2HDAC4HDAC8HDAC6HDAC1
SCHEMBL9577685 0.73 HDAC2 (0.50) HDAC2HDAC4HDAC8HDAC6HDAC1
SCHEMBL15759686 0.72 HDAC2 (0.48) HDAC2HDAC4HDAC8HDAC6HDAC1
SCHEMBL28746464 0.70 POLB (0.34)
SCHEMBL4886637 0.70
SCHEMBL2988371 0.69
SCHEMBL1357104 0.69 MCL1 (0.45)
Cyclohexene SCHEMBL31379015 0.69 HDAC2 (0.53) HDAC2HDAC4HDAC8HDAC6HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6544712-B1 Sensitivity, resist pattern profile, and aging stability; suitable to fine processing with radiations such as ultraviolet rays, excimer laser, x-rays, electron beams TOKYO OHKA KOGYO CO., LTD. (JP) 2003-04-08 US disclosed
EP-0651893-B1 HEXAHYDROXYBENZOPHENONE SULFONATE ESTERS OF DIAZONAPHTHOQUINONE SENSITIZERS AND POSITIVE PHOTORESISTS EMPLOYING SAME CLARIANT FINANCE BVI LTD (VG) 1999-01-20 EP disclosed
US-5755910-A STACKING SHEETS CARRYING IMAGES OF ONE COLOR AND RECEIVER SHEETS ON A SUPPORT, THEN HOT ROLLING AND REPEATING FOR DIFFERENT COLORED SHEETS MITSUBISHI CHEMICAL CORPORATION (JP) 1998-05-26 US disclosed