Methylene Chloride

Methylene Chloride

SCHEMBL715853

ClCCl.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl

nearest known ligand 0.30

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.30
ALDH1A1 P00352 1/20 0.30
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL758893 0.90 ALDH1A1 (0.35) TSHRALDH1A1TP53
SCHEMBL5427 0.90 ALDH1A1 (0.35) TSHRALDH1A1TP53
Water SCHEMBL28635166 0.87 ALDH1A1 (0.33) TSHRALDH1A1TP53
Ammonia Solution, Strong SCHEMBL18983394 0.87 ALDH1A1 (0.33) TSHRALDH1A1TP53
SCHEMBL22689331 0.87 ALDH1A1 (0.33) TSHRALDH1A1TP53
Bromide SCHEMBL28542014 0.87 ALDH1A1 (0.33) TSHRALDH1A1TP53
Bicarbonate SCHEMBL15874485 0.84 ALDH1A1 (0.39) TSHRALDH1A1TP53
Ethylene SCHEMBL29034469 0.84 ALDH1A1 (0.32) TSHRALDH1A1TP53
SCHEMBL926990 0.84 ALDH1A1 (0.32) TSHRALDH1A1TP53
SCHEMBL541992 0.84 ALDH1A1 (0.32) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118005573-A Activated near infrared fluorescent probe based on methylene blue and preparation method and application thereof 遵义医科大学附属医院 2024-05-10 CN claimed
CN-117209743-B Modified bisphenol AF polycarbonate material and preparation method thereof 江苏福赛乙德药业有限公司 2024-03-29 CN claimed
CN-117209743-A Modified bisphenol AF polycarbonate material and preparation method thereof 江苏福赛乙德药业有限公司 2023-12-12 CN claimed
CN-116190380-B Groove type MOS device and preparation method thereof 青岛澳芯瑞能半导体科技有限公司 2023-08-08 CN claimed
CN-116190380-A Groove type MOS device and preparation method thereof 青岛澳芯瑞能半导体科技有限公司 2023-05-30 CN claimed
CN-111793200-B Preparation method of recessive immunoliposome modified phospholipid raw material 上海易全化学有限公司 2023-05-26 CN claimed
CN-115286841-B Metal powder compound and preparation method thereof, spraying-free PC composite material and preparation method thereof, and metal-texture injection molding part 宁波公牛电器有限公司 2023-04-18 CN claimed
CN-110467582-B Lighting type near-infrared fluorescent probe for copper ion detection and preparation method thereof 浙江师范大学 2023-03-21 CN claimed
CN-114940656-B Preparation method of high-purity glibornuride 泽升科技(广州)有限公司 2023-02-17 CN claimed
CN-115286841-A Metal powder compound and preparation method thereof, spraying-free PC (polycarbonate) composite material and preparation method thereof, and metal-texture injection molding part 宁波公牛电器有限公司 2022-11-04 CN claimed
CN-114940656-A Preparation method of high-purity glibornuride 泽升科技(广州)有限公司 2022-08-26 CN claimed
CN-108250074-A Biology base carbonate-containing structure glycol polymerisable monomer and its preparation method and application 贵州大学 2018-07-06 CN claimed
CN-106008352-A Hydantoin derivative, and preparation method and application thereof 中国农业科学院植物保护研究所 2016-10-12 CN claimed
CN-118201932-A Preparation method of drug-connector conjugate 四川科伦博泰生物医药股份有限公司 2024-06-14 CN disclosed
CN-118119594-A Camptothecin derivative intermediate, preparation method and application thereof 上海弼领生物技术有限公司 2024-05-31 CN disclosed
CN-118005573-A Activated near infrared fluorescent probe based on methylene blue and preparation method and application thereof 遵义医科大学附属医院 2024-05-10 CN disclosed
CN-100369909-C N-[4(R)-(1,3-dioxane)methyl] aniline and its prepn and use SHANGHAI INST OF MEDICAMENT CA (CN) 2008-02-20 CN disclosed
CN-1673224-A N-[4(R)-(1,3-dioxane)methyl] aniline and its prepn and use SHANGHAI INST OF MEDICAMENT CA (CN) 2005-09-28 CN disclosed
US-6214505-B1 CONTAINING POLYIMIDE-CARBONATE BINDER RESIN XEROX CORPORATION 2001-04-10 US disclosed
CN-1165815-A Phenol compound and process for preparing the same TANABE SEIYAKU CO (JP) 1997-11-26 CN disclosed