Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.54 |
| ▸ | HTR2A | P28223 | 5/20 | 0.54 |
| ▸ | HTR1A | P08908 | 4/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.54 |
| ▸ | HTR2B | P41595 | 4/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.54 |
| ▸ | HTR1D | P28221 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | HTR1B | P28222 | 2/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | SPR | P35270 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
| ▸ | HTR3B | O95264 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6516528 | 0.87 | HTR2C (0.55) | HTR2CHTR2AHTR1ACYP2D6HTR2B | |
| SCHEMBL29414816 | 0.87 | HTR2C (0.55) | HTR2CHTR2AHTR1ACYP2D6HTR2B | |
| SCHEMBL6469548 | 0.84 | HTR2C (0.60) | HTR2CHTR2AHTR1ACYP2D6HTR2B | |
| SCHEMBL6978983 | 0.81 | HTR2C (0.54) | HTR2CHTR2AHTR1ACYP2D6HTR2B | |
| SCHEMBL38656762 | 0.81 | HTR2C (0.50) | HTR2CHTR2AHTR1ACYP2D6HTR2B | |
| SCHEMBL8205708 | 0.81 | HTR2C (0.57) | HTR2CHTR2AHTR1ACYP2D6HTR2B | |
| SCHEMBL7640404 | 0.81 | HTR2C (0.67) | HTR2CHTR2AHTR1ACYP2D6HTR2B | |
| SCHEMBL9094375 | 0.81 | GUSB (0.54) | HTR2ASLC6A4GUSB | |
| SCHEMBL9651541 | 0.81 | HTR2A (0.53) | HTR2CHTR2AHTR1ASLC6A4KDM4E | |
| SCHEMBL2494144 | 0.80 | HTR2C (0.52) | HTR2CHTR2AHTR1ACYP2D6HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415802-B1 | KERATINOUS FIBRES DYEING PROCESS WITH MONOHYDROXYINDOLE AND HYDROXYINDOLE-5,6-DISUBSTITUTED AND COMPOSITION | L'OREAL (FR) | 1993-03-10 | — | — | EP | claimed |
| EP-0271186-B1 | HYDROXYINDOLES AND THEIR USE IN DYEING | REPLIGEN CORPORATION (US) | 1992-12-30 | — | — | EP | claimed |
| US-5135544-A | Applying indole mixture, rinsing, applying periodate solution | L'OREAL (FR) | 1992-08-04 | — | — | US | claimed |
| US-6540791-B1 | Oxidizer, a buffer of borates and/or alkalizing agents, a stabilizer, and a hair care ingredient such as surfactant, catalyst (enzyme), thickener, or conditioner; shelf life, bleaching performance | THE PROCTER & GAMBLE COMPANY | 2003-04-01 | — | — | US | disclosed |
| WO-2001072271-A2 | STABLE ALKALINE HAIR BLEACHING AND COLORING COMPOSITIONS AND METHOD FOR USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2001-10-04 | — | — | WO | disclosed |
| EP-0271186-B1 | HYDROXYINDOLES AND THEIR USE IN DYEING | REPLIGEN CORPORATION (US) | 1992-12-30 | — | — | EP | disclosed |
| US-5135544-A | Applying indole mixture, rinsing, applying periodate solution | L'OREAL (FR) | 1992-08-04 | — | — | US | disclosed |