Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.51 |
| ▸ | FAAH | O00519 | 3/20 | 0.49 |
| ▸ | CES1 | P23141 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.47 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28441940 | 0.87 | PPARG (0.53) | MAPTRXFP1LTB4RFAAHALDH1A1 | |
| SCHEMBL28206356 | 0.87 | LTB4R (0.48) | MAPTRXFP1LTB4RFAAHCES1 | |
| SCHEMBL6372107 | 0.83 | LTB4R (0.68) | MAPTRXFP1LTB4RFAAHCES1 | |
| SCHEMBL9781113 | 0.83 | MAPT (0.55) | MAPTRXFP1LTB4RFAAHCES1 | |
| SCHEMBL27580342 | 0.83 | LTB4R (0.68) | MAPTRXFP1LTB4RFAAHCES1 | |
| SCHEMBL17748289 | 0.83 | LTB4R (0.68) | MAPTRXFP1LTB4RFAAHCES1 | |
| SCHEMBL19524628 | 0.82 | PPARG (0.43) | LTB4R | |
| SCHEMBL8954730 | 0.81 | POLB (0.49) | MAPTRXFP1LTB4RFAAHCES1 | |
| SCHEMBL5619673 | 0.81 | MAPT (0.52) | MAPTRXFP1LTB4RFAAHCES1 | |
| SCHEMBL28303471 | 0.81 | MAPT (0.52) | MAPTRXFP1LTB4RFAAHCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0940383-B1 | Method for the selective alkylation of aldehydes with organozinc compounds | CHEMETALL GMBH (DE) | 2003-06-18 | — | — | EP | disclosed |
| US-6184404-B1 | THE ORGANOZINC COMPOUND HAVING A LIGAND WHICH IS TRANSFERRED TO THE ALDEHYDE, THE OTHER LIGAND ACTS AS SO-CALLED DUMMY LIGAND; PRODUCING FUNCTIONALIZED SECONDARY ALCOHOLS IN GOOD YIELDS AND VERY GOOD ENANTIOMERIC PURITY; MATERIALS HANDLING | METALLGESELLSCHAFT AKTIENGESELLSCHAFT (DE) | 2001-02-06 | — | — | US | disclosed |
| EP-0940383-A2 | Method for the selective alkylation of aldehydes with organozinc compounds | Metallgesellschaft Aktiengesellschaft (DE) | 1999-09-08 | — | — | EP | disclosed |