Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | CLK3 | P49761 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | PNCK | Q6P2M8 | 1/20 | 0.33 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.33 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1323657 | 0.76 | TDP1 (0.45) | CYP1A2LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL9692146 | 0.76 | — | — | |
| SCHEMBL2893718 | 0.73 | HSD17B10 (0.41) | HSD17B10CYP1A2LMNATHRBBLM | |
| SCHEMBL14641228 | 0.73 | DYRK1A (0.36) | HSD17B10CYP1A2LMNATHRBBLM | |
| SCHEMBL9104761 | 0.73 | MAPT (0.40) | LMNADYRK1AKMT2AMEN1MAPT | |
| SCHEMBL28520422 | 0.73 | — | — | |
| SCHEMBL32909 | 0.73 | — | — | |
| SCHEMBL10351402 | 0.71 | HSD17B10 (0.39) | HSD17B10CYP1A2LMNATHRBBLM | |
| SCHEMBL8213611 | 0.71 | HSD17B10 (0.39) | HSD17B10CYP1A2LMNATHRBBLM | |
| SCHEMBL2491794 | 0.71 | ALDH1A1 (0.47) | HSD17B10CYP1A2LMNATHRBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114108367-B | Method for preparing modified cationic starch by dry method | 上海东升新材料有限公司 | 2023-03-17 | — | — | CN | claimed |
| CN-114958320-A | Silicate-cholate-hydroxypropyl guar gel for profile control and preparation method thereof | 滨州学院 | 2022-08-30 | — | — | CN | claimed |
| CN-114108367-A | Method for preparing modified cationic starch by dry method | 上海东升新材料有限公司 | 2022-03-01 | — | — | CN | claimed |
| US-20240425478-A1 | CYCLOPENTYLPYRAZOLE CDK2 INHIBITORS | GENENTECH INC (US) | 2024-12-26 | — | — | US | disclosed |
| CN-113583144-B | Preparation method and application of one-way memory flocculant | 石河子大学 | 2023-07-18 | — | — | CN | disclosed |
| CN-114108367-B | Method for preparing modified cationic starch by dry method | 上海东升新材料有限公司 | 2023-03-17 | — | — | CN | disclosed |
| CN-114958320-A | Silicate-cholate-hydroxypropyl guar gel for profile control and preparation method thereof | 滨州学院 | 2022-08-30 | — | — | CN | disclosed |
| CN-114108367-A | Method for preparing modified cationic starch by dry method | 上海东升新材料有限公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-113583144-A | Preparation method and application of one-way memory type flocculating agent | 石河子大学 | 2021-11-02 | — | — | CN | disclosed |
| EP-3355699-B1 | BICYCLIC COMPOUND AND USE THEREOF FOR INHIBITING SUV39H2 | ONCOTHERAPY SCIENCE INC (JP) | 2021-03-31 | — | — | EP | disclosed |
| US-20180273529-A1 | BICYCLIC COMPOUND AND USE THEREOF FOR INHIBITING SUV39H2 | ONCOTHERAPY SCIENCE, INC. (JP) | 2018-09-27 | — | — | US | disclosed |
| CN-101448397-A | Selective benzylamine derivatives and their use as cholesteryl ester transfer protein inhibitors | REDDY US THERAPEUTICS INC (US) | 2009-06-03 | — | — | CN | disclosed |
| EP-1981342-A1 | SELECTIVE BENZYLAMINE DERIVATIVES AND THEIR UTILITY AS CHOLESTEROL ESTER-TRANSFER PROTEIN INHIBITORS | Reddy US Therapeutics, Inc. (US) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007075194-A1 | SELECTIVE BENZYLAMINE DERIVATIVES AND THEIR UTILITY AS CHOLESTEROL ESTER-TRANSFER PROTEIN INHIBITORS | REDDY US THERAPEUTICS, INC. (US) | 2007-07-05 | — | — | WO | disclosed |
| WO-2007075194-A1 | SELECTIVE BENZYLAMINE DERIVATIVES AND THEIR UTILITY AS CHOLESTEROL ESTER-TRANSFER PROTEIN INHIBITORS | REDDY US THERAPEUTICS, INC. (US) | 2007-07-05 | — | — | WO | disclosed |
| US-20070015758-A1 | Novel benzylamine derivatives and their utility as cholesterol ester-transfer protein inhibitors | DR. REDDY'S LABORATORIES LTD. (IN) | 2007-01-18 | — | — | US | disclosed |
| US-20070015758-A1 | Novel benzylamine derivatives and their utility as cholesterol ester-transfer protein inhibitors | DR. REDDY'S LABORATORIES LTD. (IN) | 2007-01-18 | — | — | US | disclosed |
| US-20070015758-A1 | Novel benzylamine derivatives and their utility as cholesterol ester-transfer protein inhibitors | DR. REDDY'S LABORATORIES LTD. (IN) | 2007-01-18 | — | — | US | disclosed |
| US-4753940-A | PARASITICIDE, ANTHELMINTIC | CIBA-GEIGY CORPORATION (US) | 1988-06-28 | — | — | US | disclosed |
| US-4016013-A | OR CARBONITRIDESDECOMPOSITION OF TRIAZINE OR PYRIMIDINE COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1977-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240425478-A1 | CYCLOPENTYLPYRAZOLE CDK2 INHIBITORS | CDK2, CCNI, CDK20 | HSD17B10 3403/4885CYP1A2 960/4885LMNA 1610/4885 |
| US-20180273529-A1 | BICYCLIC COMPOUND AND USE THEREOF FOR INHIBITING SUV39H2 | SUV39H2, SUV39H1, EZH1 | HSD17B10 664/4885CYP1A2 3455/4885LMNA 3773/4885 |
| US-20070015758-A1 | Novel benzylamine derivatives and their utility as cholesterol ester-transfer protein inhibitors | CETP, NPC1, DBI | HSD17B10 354/4885CYP1A2 2839/4885LMNA 1125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.