Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4904318 | 0.97 | TSHR (0.39) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL7161753 | 0.94 | TSHR (0.37) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL26927350 | 0.86 | TSHR (0.39) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL9019108 | 0.84 | ALDH1A1 (0.42) | TSHRMAPK1ALDH1A1 | |
| SCHEMBL22204608 | 0.84 | TSHR (0.33) | TSHRMAPK1ALDH1A1 | |
| SCHEMBL18104531 | 0.84 | TSHR (0.33) | TSHRMAPK1ALDH1A1 | |
| SCHEMBL2499893 | 0.84 | ALDH1A1 (0.42) | TSHRMAPK1ALDH1A1 | |
| SCHEMBL8056847 | 0.84 | MEN1 (0.55) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL8987906 | 0.82 | — | — | |
| Ethylene Glycol SCHEMBL28135742 | 0.82 | ALDH1A1 (0.40) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6585821-B1 | Measuring absorption to determine reaction completion and terminating heating of lead acetate and diethylene glycol ethyl ether solution; lead di(ethylene glycol)ethyl ether precursor for lead germanium oxide (PGO) production | SHARP LABORATORIES OF AMERICA, INC. | 2003-07-01 | — | — | US | claimed |
| US-6585821-B1 | Measuring absorption to determine reaction completion and terminating heating of lead acetate and diethylene glycol ethyl ether solution; lead di(ethylene glycol)ethyl ether precursor for lead germanium oxide (PGO) production | SHARP LABORATORIES OF AMERICA, INC. | 2003-07-01 | — | — | US | disclosed |