Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.31 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.31 |
| ▸ | ITGAL | P20701 | 1/20 | 0.31 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7168221 | 0.88 | FFAR4 (0.33) | SMN1; SMN2NPC1CYP1A2CYP2C19RAB9A | |
| SCHEMBL372145 | 0.85 | ITGB2 (0.39) | LMNAALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL19928557 | 0.84 | DRD1 (0.36) | LMNASMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL3136613 | 0.82 | ITGB2 (0.39) | LMNAALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL20351197 | 0.81 | ITGB2 (0.38) | LMNASMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL3133241 | 0.81 | ITGB2 (0.38) | LMNASMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL13243539 | 0.81 | ITGB2 (0.38) | LMNASMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL9913796 | 0.81 | DRD1 (0.36) | LMNASMN1; SMN2GAAITGB2ICAM1 | |
| SCHEMBL3132985 | 0.78 | ITGB2 (0.46) | LMNAPKMSMN1; SMN2GAAITGB2 | |
| SCHEMBL18979231 | 0.77 | DRD1 (0.35) | LMNAPKMTSHRSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095946-B1 | Optically active diphosphine compound, production intermediates therefor, transition metal complex containing the compound as ligand and asymmetric hydrogenation catalyst containing the complex | TAKASAGO PERFUMERY CO LTD (JP) | 2003-08-27 | — | — | EP | disclosed |
| US-6333291-B1 | USEFUL AS A LIGAND OF CATALYSTS FOR ASYMMETRIC SYNTHESIS REACTIONS SUCH AS ASYMMETRIC HYDROGENATION REACTION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2001-12-25 | — | — | US | disclosed |
| EP-1095946-A1 | Optically active diphosphine compound, production intermediates therefor, transition metal complex containing the compound as ligand and asymmetric hydrogenation catalyst containing the complex | Takasago International Corporation (JP) | 2001-05-02 | — | — | EP | disclosed |