Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 9/20 | 0.60 |
| ▸ | CA2 | P00918 | 9/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6087112 | 0.78 | CA1 (0.63) | CA1CA2PKMMEN1LMNA | |
| SCHEMBL6086434 | 0.78 | CA1 (0.63) | CA1CA2CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL6087817 | 0.77 | CA1 (0.58) | CA1CA2CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL6087495 | 0.77 | SMN1; SMN2 (0.68) | CA1CA2PKMMEN1LMNA | |
| SCHEMBL6073362 | 0.76 | CA1 (0.62) | CA1CA2PKMMEN1KMT2A | |
| SCHEMBL6086574 | 0.74 | SMN1; SMN2 (0.59) | CA1CA2MAPTPKMMEN1 | |
| SCHEMBL6087517 | 0.74 | CA2 (0.55) | CA1CA2PKMMEN1LMNA | |
| SCHEMBL6085986 | 0.74 | CA1 (0.55) | CA1CA2CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL6087557 | 0.73 | CA1 (0.57) | CA1CA2PKMMEN1LMNA | |
| SCHEMBL6087640 | 0.73 | CA2 (0.57) | CA1CA2MAPTMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0939627-B1 | PENTAFLUOROBENZENESULFONAMIDES AND ANALOGS | TULARIK INC (US) | 2003-09-10 | — | — | EP | claimed |