Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27817357 | 0.82 | MEN1 (0.42) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL18131885 | 0.77 | P2RX7 (0.39) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL22496025 | 0.77 | MEN1 (0.41) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL27629796 | 0.75 | MEN1 (0.41) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL4634211 | 0.75 | CYP1A2 (0.39) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL5418324 | 0.74 | P2RX7 (0.45) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL28003009 | 0.74 | MEN1 (0.42) | MEN1KMT2AALDH1A1LMNAMAPT | |
| Ketopinic Acid SCHEMBL2735035 | 0.74 | KMT2A (0.53) | MEN1KMT2AALDH1A1LMNAMAPT | |
| Ketopinic Acid SCHEMBL16691935 | 0.74 | KMT2A (0.53) | MEN1KMT2AALDH1A1LMNAMAPT | |
| Ketopinic Acid SCHEMBL21458724 | 0.74 | KMT2A (0.53) | MEN1KMT2AALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6589945-B1 | Treating human skin by inhibiting serine protease formation involving contacting the skin with a composition containing a sterol sulfate. | COGNIS DEUTSCHLAND GMBH & CO. KG (DE) | 2003-07-08 | — | — | US | disclosed |