Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CCR2 | P41597 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17064985 | 0.88 | GRN (0.33) | HTTPOLBKDM4EKLKB1MAPT | |
| SCHEMBL27842913 | 0.76 | HTT (0.34) | HTTNPC1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL1380340 | 0.73 | CCNC (0.34) | HTTKMT2AL3MBTL1FLT1KDR | |
| Hydrochloric Acid SCHEMBL30613390 | 0.71 | CCNC (0.33) | HTTKMT2AL3MBTL1 | |
| SCHEMBL30700394 | 0.71 | HCAR3 (0.39) | HTTPOLBKMT2AL3MBTL1NPC1 | |
| SCHEMBL26112334 | 0.69 | F2 (0.47) | POLBMEN1KMT2AL3MBTL1CYP1A2 | |
| Chlorobenzene SCHEMBL11116080 | 0.67 | TSHR (0.55) | HTTMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL17869333 | 0.67 | GRN (0.51) | CCR2POLBMEN1KMT2ARECQL | |
| SCHEMBL20916894 | 0.66 | TSHR (0.48) | HTTCCR2MEN1KMT2ANPC1 | |
| SCHEMBL14699330 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341780-A2 | SUBSTITUTED HETEROCYCLIC PHTHALIC ACID DIAMIDE ARTHROPODICIDES | E. I. du Pont de Nemours and Company (US) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002048137-A2 | SUBSTITUTED HETEROCYCLIC PHTHALIC ACID DIAMIDE ARTHROPODICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-06-20 | — | — | WO | disclosed |