Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7160701 | 1.00 | SIGMAR1 (0.45) | SIGMAR1ALDH1A1HTR2AHRH1S1PR2 | |
| SCHEMBL7162655 | 0.99 | SIGMAR1 (0.48) | SIGMAR1ALDH1A1HTR2AHRH1S1PR2 | |
| SCHEMBL7160527 | 0.99 | SIGMAR1 (0.48) | SIGMAR1ALDH1A1HTR2AHRH1S1PR2 | |
| SCHEMBL7165897 | 0.99 | SIGMAR1 (0.48) | SIGMAR1ALDH1A1HTR2AHRH1S1PR2 | |
| SCHEMBL7160533 | 0.99 | SIGMAR1 (0.48) | SIGMAR1ALDH1A1HTR2AHRH1S1PR2 | |
| SCHEMBL7165202 | 0.99 | SIGMAR1 (0.48) | SIGMAR1ALDH1A1HTR2AHRH1S1PR2 | |
| SCHEMBL7161637 | 0.99 | SIGMAR1 (0.48) | SIGMAR1ALDH1A1HTR2AHRH1S1PR2 | |
| SCHEMBL7161631 | 0.99 | SIGMAR1 (0.48) | SIGMAR1ALDH1A1HTR2AHRH1S1PR2 | |
| SCHEMBL7165198 | 0.99 | SIGMAR1 (0.48) | SIGMAR1ALDH1A1HTR2AHRH1S1PR2 | |
| SCHEMBL7165890 | 0.99 | SIGMAR1 (0.48) | SIGMAR1ALDH1A1HTR2AHRH1S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6552176-B2 | One pot | G. D. SEARLE & CO. | 2003-04-22 | — | — | US | disclosed |
| US-20010019837-A1 | PROCESS FOR MICROBIALLY OXIDIZING N-SUBSTITUTED GLUCAMINES | GRABNER ROY WALTER (US) | 2001-09-06 | — | — | US | disclosed |
| US-5916784-A | Process for microbially oxidizing N-substituted glucamines | G.D. SEARLE & COMPANY (US) | 1999-06-29 | — | — | US | disclosed |
| US-5610039-A | OXIDIZING A GLUCAMINE TO PRODUCE AN INTERMEDIATE COMPOUND AND REDUCING INTERMEDIATE | G. D. SEARLE & CO. (US) | 1997-03-11 | — | — | US | disclosed |
| US-5602013-A | Process for producing N-substituted-1-deoxynojirimycin | G. D. SEARLE & CO. (US) | 1997-02-11 | — | — | US | disclosed |
| EP-0477160-B1 | Process for producing N-substituted-1-deoxynojirimycin | MONSANTO CO (US) | 1996-04-24 | — | — | EP | disclosed |
| EP-0477160-A1 | Process for producing N-substituted-1-deoxynojirimycin | MONSANTO COMPANY (US) | 1992-03-25 | — | — | EP | disclosed |