Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 9/20 | 0.61 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ESRRG | P62508 | 1/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL14157254 | 0.98 | TAAR1 (0.59) | TAAR1CYP2A6CYP1A2MAOBKCNH2 | |
| SCHEMBL15125588 | 0.94 | MAOB (0.63) | TAAR1CYP2A6CYP1A2MAOBKCNH2 | |
| SCHEMBL2879490 | 0.86 | KCNH2 (0.58) | TAAR1KCNH2HTR2AESRRGSIGMAR1 | |
| SCHEMBL7456580 | 0.85 | KCNH2 (0.59) | KCNH2ESRRGSIGMAR1 | |
| SCHEMBL20748225 | 0.85 | KCNH2 (0.61) | TAAR1KCNH2HTR2AESRRGSIGMAR1 | |
| SCHEMBL27262014 | 0.84 | KCNH2 (0.50) | TAAR1KCNH2ESRRGLOXL2SIGMAR1 | |
| SCHEMBL7875335 | 0.84 | TAAR1 (0.65) | TAAR1CYP2A6CYP1A2MAOBHTR2A | |
| SCHEMBL10666169 | 0.83 | KCNH2 (0.59) | TAAR1KCNH2HTR2AESRRGSIGMAR1 | |
| SCHEMBL7684129 | 0.82 | TAAR1 (0.58) | TAAR1CYP2A6CYP1A2MAOBHTR2A | |
| SCHEMBL31573982 | 0.80 | KCNH2 (0.67) | KCNH2ESRRGSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114420852-A | Preparation method of pure-phase RP perovskite film | 河北工业大学 | 2022-04-29 | — | — | CN | claimed |
| EP-2074089-B1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2013-09-18 | — | — | EP | claimed |
| US-8222248-B2 | Organic compounds | NOVARTIS AG (CH) | 2012-07-17 | — | — | US | claimed |
| EP-2074089-A2 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2009-07-01 | — | — | EP | claimed |
| WO-2008048991-A2 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2008-04-24 | — | — | WO | claimed |
| US-20230312577-A1 | DUAL KINASE-BROMODOMAIN INHIBITORS | MONASH UNIVERSITY (AU) | 2023-10-05 | — | — | US | disclosed |
| US-20230312577-A1 | DUAL KINASE-BROMODOMAIN INHIBITORS | MONASH UNIVERSITY (AU) | 2023-10-05 | — | — | US | disclosed |
| US-20220332695-A1 | UREA DERIVATIVES AS CB1 ALLOSTERIC MODULATORS | RESEARCH TRIANGLE INSTITUTE | 2022-10-20 | — | — | US | disclosed |
| CN-114420852-A | Preparation method of pure-phase RP perovskite film | 河北工业大学 | 2022-04-29 | — | — | CN | disclosed |
| EP-3144303-A1 | 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | Array Biopharma, Inc. (US) | 2017-03-22 | — | — | EP | disclosed |
| US-9556139-B2 | 6-substituted phenoxychroman carboxylic acid derivatives | ARRAY BIOPHARMA INC. (US) | 2017-01-31 | — | — | US | disclosed |
| WO-2016109501-A1 | AMIDE COMPOUNDS AS TRYPTOPHAN HYDROXYLASE INHIBITORS | KAROS PHARMACEUTICALS, INC. (US) | 2016-07-07 | — | — | WO | disclosed |
| US-6015925-A | TREATING MYCOSIS | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2000-01-18 | — | — | US | disclosed |
| US-5350749-A | Fungicides, insecticides and miticides | DOWELANCO (US) | 1994-09-27 | — | — | US | disclosed |
| EP-0593438-A1 | FUNGICIDAL COMPOSITIONS, FUNGICIDAL COMPOUNDS, THEIR PRODUCTION AND USE | DOWELANCO (US) | 1994-04-27 | — | — | EP | disclosed |
| US-5292743-A | Substituted guanidines; low phytotoxicity; agricultural use | DOWELANCO (US) | 1994-03-08 | — | — | US | disclosed |
| US-5240916-A | Fungicides | DOWELANCO (US) | 1993-08-31 | — | — | US | disclosed |
| US-5034393-A | Fungicides for plants | DOWELANCO (US) | 1991-07-23 | — | — | US | disclosed |
| WO-1991005473-A1 | FUNGICIDAL COMPOSITIONS, FUNGICIDAL COMPOUNDS, THEIR PRODUCTION AND USE | DOW CHEMICAL COMPANY LIMITED (GB) | 1991-05-02 | — | — | WO | disclosed |
| EP-0410762-A1 | Naphthyridine derivatives | DowElanco (US) | 1991-01-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230312577-A1 | DUAL KINASE-BROMODOMAIN INHIBITORS | MAP2K2, BRPF3, BRDT | TAAR1 4392/4885CYP2A6 4761/4885CYP1A2 4767/4885 |
| US-20220332695-A1 | UREA DERIVATIVES AS CB1 ALLOSTERIC MODULATORS | CNR1, CNR2, GPR119 | TAAR1 28/4885CYP2A6 332/4885CYP1A2 517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.