Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6767239 | 0.91 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL7160837 | 0.90 | KMT2A (0.51) | ALDH1A1SMN1; SMN2KMT2AMEN1TDP1 | |
| SCHEMBL6771746 | 0.86 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2KMT2AMAPTPOLB | |
| SCHEMBL6765259 | 0.82 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2KMT2AOPRM1 | |
| SCHEMBL6764637 | 0.80 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2KMT2AMEN1TDP1 | |
| SCHEMBL6766824 | 0.79 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL9045718 | 0.79 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL9213271 | 0.78 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL6771072 | 0.78 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2KMT2AMAPTPOLB | |
| SCHEMBL6762566 | 0.78 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6555567-B1 | 2-oxo-3-aryl-4-hydroxy-1-aza-8-thiaspiro(4.5)decane derivatives of given formula; use as arthropodicide or nematicide | BAYER AKTIENGESELLSCHAFT (DE) | 2003-04-29 | — | — | US | disclosed |