Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 5/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25790183 | 0.85 | FOLH1 (0.40) | FOLH1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL716120 | 0.81 | FOLH1 (0.47) | FOLH1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL20150964 | 0.81 | FOLH1 (0.47) | FOLH1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL136522 | 0.81 | FOLH1 (0.41) | FOLH1HDAC3HDAC4HDAC1HDAC7 | |
| Bromide SCHEMBL7750130 | 0.80 | FOLH1 (0.46) | FOLH1HDAC3HDAC4HDAC1HDAC7 | |
| Bromide SCHEMBL7750134 | 0.80 | FOLH1 (0.46) | FOLH1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL716119 | 0.80 | FOLH1 (0.37) | FOLH1 | |
| SCHEMBL7750174 | 0.79 | MAPT (0.41) | FOLH1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL634713 | 0.77 | MAPT (0.34) | — | |
| SCHEMBL14823545 | 0.75 | FOLH1 (0.43) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9499862-B2 | Phospholinked dye analogs with an amino acid linker | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2016-11-22 | — | — | US | disclosed |
| US-20150197794-A1 | Phospholinked Dye Analogs with an Amino Acid Linker | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2015-07-16 | — | — | US | disclosed |
| US-8993737-B2 | Phospholinked dye analogs with an amino acid linker | PACIFIC BIOSCIENCES, INC. (US) | 2015-03-31 | — | — | US | disclosed |
| US-20120052507-A1 | PHOSPHOLINKED DYE ANALOGS WITH AN AMINO ACID LINKER | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120052507-A1 | PHOSPHOLINKED DYE ANALOGS WITH AN AMINO ACID LINKER | CHAMP1, MTAP, INCENP | FOLH1 614/4885HDAC3 4748/4885HDAC4 4727/4885 |
| US-20150197794-A1 | Phospholinked Dye Analogs with an Amino Acid Linker | INCENP, CHAMP1, PNKP | FOLH1 786/4885HDAC3 4189/4885HDAC4 4324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.