Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | KLK7 | P49862 | 1/20 | 0.56 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | IDH1 | O75874 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.51 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7165421 | 0.86 | KMT2A (0.58) | MEN1KMT2AMAPTNPSR1GAA | |
| SCHEMBL18025321 | 0.80 | MAPT (0.76) | MEN1KMT2AMAPTGAACHRNA7 | |
| SCHEMBL4555009 | 0.80 | MAPT (0.76) | MEN1KMT2AMAPTCHRNA7KDM4E | |
| SCHEMBL7164667 | 0.79 | MEN1 (0.64) | MEN1KMT2AMAPTNPSR1GAA | |
| SCHEMBL6815584 | 0.79 | KMT2A (0.63) | MEN1KMT2AMAPTNPSR1GAA | |
| SCHEMBL6816388 | 0.78 | MAPT (0.74) | MEN1KMT2AMAPTNPSR1CHRNA7 | |
| SCHEMBL7162969 | 0.78 | MEN1 (0.78) | MEN1KMT2AMAPTNPSR1GAA | |
| SCHEMBL6816373 | 0.76 | MAPT (0.74) | MEN1KMT2AMAPTNPSR1CHRNA7 | |
| SCHEMBL4555949 | 0.76 | MAPT (0.70) | MEN1KMT2AMAPTCHRNA7KDM4E | |
| SCHEMBL6816576 | 0.76 | KMT2A (0.80) | MEN1KMT2AMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6555561-B2 | N-(5-((((5-Chloro-2,4-dimethoxyphenyl)amino)thioxomethyl)-amino)-2 -pyridinyl)-2-methylbenzamide, for example; inhibiting replication of a herpes virus | WYETH | 2003-04-29 | — | — | US | disclosed |