Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | GAA | P10253 | 3/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 9/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7162969 | 0.92 | MEN1 (0.78) | MEN1KMT2AGAANPSR1MAPT | |
| SCHEMBL7162179 | 0.84 | KMT2A (0.54) | MEN1KMT2AGAANPSR1MAPT | |
| SCHEMBL7165683 | 0.83 | MAPT (0.55) | MEN1KMT2AGAANPSR1MAPT | |
| SCHEMBL7163728 | 0.83 | KDM4E (0.72) | MEN1KMT2AGAANPSR1MAPT | |
| SCHEMBL7165775 | 0.81 | MAPT (0.67) | MEN1KMT2AGAANPSR1MAPT | |
| SCHEMBL6812142 | 0.81 | MAPT (0.67) | MEN1KMT2AGAANPSR1MAPT | |
| SCHEMBL7939055 | 0.81 | MAPT (0.70) | MEN1KMT2AGAANPSR1MAPT | |
| SCHEMBL6815648 | 0.81 | MAPT (0.70) | MEN1KMT2AGAANPSR1MAPT | |
| SCHEMBL6815144 | 0.80 | MAPT (0.62) | MEN1KMT2AGAANPSR1MAPT | |
| SCHEMBL6815565 | 0.80 | MAPT (0.62) | MEN1KMT2AGAANPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6555561-B2 | N-(5-((((5-Chloro-2,4-dimethoxyphenyl)amino)thioxomethyl)-amino)-2 -pyridinyl)-2-methylbenzamide, for example; inhibiting replication of a herpes virus | WYETH | 2003-04-29 | — | — | US | disclosed |