SCHEMBL716274

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL719271	0.90	OPRM1 (0.41)	OPRM1RCE1HDAC6SLC6A2SLC6A4
	SCHEMBL717386	0.83	GCG (0.46)	OPRM1RCE1
	SCHEMBL718796	0.83	RCE1 (0.53)	OPRM1RCE1
	SCHEMBL719577	0.82	GCGR (0.37)	OPRM1RCE1HDAC6ABL1RIN1
	SCHEMBL719013	0.82	GCGR (0.37)	OPRM1RCE1HDAC6ABL1RIN1
	SCHEMBL719941	0.82	TEAD4 (0.39)	RCE1HDAC6ABL1RIN1
	SCHEMBL718994	0.81	RCE1 (0.38)	OPRM1RCE1HDAC6SLC6A2SLC6A4
	SCHEMBL718454	0.81	GCGR (0.38)	RCE1HDAC6ABL1RIN1
	SCHEMBL3110198	0.80	HDAC6 (0.36)	RCE1HDAC6ABL1RIN1
	SCHEMBL3113000	0.80	RCE1 (0.39)	RCE1HDAC6ABL1RIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.