Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8522264 | 0.92 | — | — | |
| SCHEMBL7163171 | 0.85 | — | — | |
| SCHEMBL7160155 | 0.77 | ALDH1A1 (0.45) | KDM4EMAPTHTTTSHRALDH1A1 | |
| SCHEMBL7374814 | 0.72 | TP53 (0.43) | TP53RXFP1HSD17B10KDM4EMAPT | |
| SCHEMBL3848312 | 0.68 | CYP11B1 (0.38) | TSHRL3MBTL1MEN1KMT2A | |
| SCHEMBL8386864 | 0.67 | CYP11B1 (0.31) | L3MBTL1 | |
| SCHEMBL26326405 | 0.66 | CYP11B1 (0.33) | TP53MAPT | |
| SCHEMBL1562700 | 0.66 | MAPT (0.45) | TP53HSD17B10KDM4EMAPTTSHR | |
| SCHEMBL8387437 | 0.66 | CYP11B1 (0.39) | TP53MAPTHTTTSHRL3MBTL1 | |
| SCHEMBL23532128 | 0.65 | CYP11B1 (0.36) | TP53TSHRALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934286-B1 | 3-ALKOXYISOXAZOL-4-YL-SUBSTITUTED 2-AMINO CARBOXYLIC ACID COMPOUNDS | LUNDBECK & CO AS H (DK) | 2003-01-08 | — | — | EP | disclosed |
| US-6200999-B1 | ALZHEIMER*S, HUNTINGTON*S, AND PARKINSON*S DISEASE; ANTIEPILEPTIC, ANALGESIC, ANXIOLYTIC, ANTIISCHEMIC AND ANTIDEPRESSANT AGENTS; NMDA AND AMPA RECEPTOR LIGANDS | H. LUNDBECK A/S (DK) | 2001-03-13 | — | — | US | disclosed |
| EP-0934286-A1 | 3-ALKOXYISOXAZOL-4-YL-SUBSTITUTED 2-AMINO CARBOXYLIC ACID COMPOUNDS | H. LUNDBECK A/S (DK) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998015542-A1 | 3-ALKOXYISOXAZOL-4-YL-SUBSTITUTED 2-AMINO CARBOXYLIC ACID COMPOUNDS | H. LUNDBECK A/S (DK) | 1998-04-16 | — | — | WO | disclosed |