Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.60 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.59 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.59 |
| ▸ | NSD3 | Q9BZ95 | 7/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | PI4KA | P42356 | 1/20 | 0.55 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.55 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.55 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | NSD2 | O96028 | 6/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4364344 | 0.86 | ADORA2A (0.70) | FGFR1SLC22A6ADORA2AADORA1ADORA2B | |
| SCHEMBL16229940 | 0.85 | FGFR1 (0.57) | FGFR1SLC22A6ADORA2AADORA1ADORA2B | |
| SCHEMBL8401399 | 0.85 | FGFR1 (0.43) | FGFR1SLC22A6ADORA2AADORA1ADORA2B | |
| SCHEMBL3421828 | 0.85 | ADORA2A (0.62) | FGFR1SLC22A6ADORA2AADORA1ADORA2B | |
| SCHEMBL16229933 | 0.81 | FGFR1 (0.53) | FGFR1SLC22A6ADORA2AADORA1ADORA2B | |
| SCHEMBL15085171 | 0.81 | SLC22A6 (0.69) | FGFR1SLC22A6ADORA2AADORA1ADORA2B | |
| SCHEMBL28296132 | 0.81 | ADORA2A (0.59) | FGFR1SLC22A6ADORA2AADORA1ADORA2B | |
| SCHEMBL2032130 | 0.80 | FGFR1 (0.62) | FGFR1SLC22A6ADORA2AADORA1ADORA2B | |
| SCHEMBL28062940 | 0.79 | CYP3A4 (0.60) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL28195884 | 0.78 | ADORA2A (0.72) | FGFR1SLC22A6ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106317115-A | Preparation method of adefovir | 天津市亨必达化学合成物有限公司 | 2017-01-11 | — | — | CN | claimed |
| CN-106317115-A | Preparation method of adefovir | 天津市亨必达化学合成物有限公司 | 2017-01-11 | — | — | CN | disclosed |
| US-6555676-B2 | Antitumor agents | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2003-04-29 | — | — | US | disclosed |
| US-6399589-B1 | VIRICIDES; ANTITUMOR AGENTS | ISIS PHARMACEUTICALS, INC. | 2002-06-04 | — | — | US | disclosed |
| US-6020482-A | Phosphotriester type biologically active compounds | CENTER NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2000-02-01 | — | — | US | disclosed |
| US-5849905-A | Biologically active phosphotriester-type nucleosides and methods for preparing same | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1998-12-15 | — | — | US | disclosed |
| US-5770725-A | USES NOVEL GROUP, CHARACTERIZED BY THE PRESENCE OF-S-S-AND/OR S-C=Z (Z=O OR S) ENZYME LABILE BONDS WHICH LEADS, AFTER ENZYMATIC ACTIVATION, TO THE FORMATION OF UNSTABLE INTERMEDIATE WHICH RELEASES MONOPHOSPHATE OR MONOPHOSPHONATE | CENTER NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1998-06-23 | — | — | US | disclosed |
| EP-0642528-B1 | PHOSPHOTRIESTER-TYPE BIOLOGICALLY ACTIVE COMPOUNDS | CENTRE NAT RECH SCIENT (FR) | 1997-01-15 | — | — | EP | disclosed |
| EP-0642528-A1 | PHOSPHOTRIESTER-TYPE BIOLOGICALLY ACTIVE COMPOUNDS. | CENTRE NAT RECH SCIENT (FR) | 1995-03-15 | — | — | EP | disclosed |
| WO-1993024510-A1 | PHOSPHOTRIESTER-TYPE BIOLOGICALLY ACTIVE COMPOUNDS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1993-12-09 | — | — | WO | disclosed |