Pyruvate

Pyruvate

SCHEMBL7164615

CC(=O)C(=O)O.CC(N)P(=O)(O)O

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LAP3 P28838 4/20 0.46
ANPEP P15144 3/20 0.41
ERAP1 Q9NZ08 1/20 0.41
GRIN2D O15399 1/20 0.41
GRIN3B O60391 1/20 0.41
GRIN1 Q05586 1/20 0.41
GRIN2A Q12879 1/20 0.41
GRIN2B Q13224 1/20 0.41
GRIN2C Q14957 1/20 0.41
GRIN3A Q8TCU5 1/20 0.41
ALDH1A1 P00352 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
METAP1 P53582 1/20 0.37
SLC7A5 Q01650 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6257829 0.83
SCHEMBL6662622 0.83
SCHEMBL242135 0.83
Hydrochloric Acid SCHEMBL9619821 0.80
Pyruvate SCHEMBL21145071 0.80 SLC7A5 (0.45) SLC7A5
SCHEMBL23302894 0.80
Bromide SCHEMBL7623997 0.80
Hydrochloric Acid SCHEMBL9789760 0.80
SCHEMBL28861534 0.80
SCHEMBL28275449 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6562958-B1 Nucleotide sequences coding polypeptide for use in the treatment and prevention of infections GENOME THERAPEUTICS CORPORATION 2003-05-13 US disclosed