SCHEMBL6662622

SCHEMBL6662622

C[C@@H](N)P(=O)(O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6257829 1.00
SCHEMBL242135 1.00
Bromide SCHEMBL7623997 0.96
Hydrochloric Acid SCHEMBL9619821 0.96
Hydrochloric Acid SCHEMBL9789760 0.96
SCHEMBL23302894 0.96
SCHEMBL28861534 0.96
SCHEMBL28275449 0.96
Phosphonic Acid SCHEMBL9791044 0.87 LAP3 (0.50)
Pyruvate SCHEMBL7164615 0.83 LAP3 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106459148-A Antimicrobial compounds 生物梅里埃公司 2017-02-22 CN disclosed
EP-0877028-B1 PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE 1-AMINOPHOSPHONIC ACID DERIVATIVES AND NOVEL PHOSPHONATE COMPOUNDS HOKKO CHEM IND CO (JP) 2004-08-25 EP disclosed
EP-1091958-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2001-04-18 EP disclosed
US-6084123-A REACTING AN IMINE WITH A PHOSPHONIC ACID ESTER USING AN ASYMMETRIC CATALYST OF A RARE EARTH METAL/ALKALI METAL-BINAPHTHOL COMPLEX; HYDROGENATION AND ACIDOLYSIS HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) 2000-07-04 US disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed
EP-0877028-A1 PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE 1-AMINOPHOSPHONIC ACID DERIVATIVES AND NOVEL PHOSPHONATE COMPOUNDS HOKKO CHEMICAL INDUSTRY CO. LTD. (JP) 1998-11-11 EP disclosed
EP-0176068-B1 PROCESS FOR THE PREPARATION OF THE STEREOISOMERS OF 1-AMINO-ALKYLPHOSPHONIC OR 1-AMINO-ALKYLPHOSPHINIC ACIDS Roche Diagnostics GmbH (DE) 1991-03-06 EP disclosed
US-4859602-A ENZYMATIC RESOLUTION USING PENICILLIN AMIDASE BOEHRINGER MANNHEIM GMBH (DE) 1989-08-22 US disclosed
EP-0176068-A2 Process for the preparation of the stereoisomers of 1-amino-alkylphosphonic or 1-amino-alkylphosphinic acids Roche Diagnostics GmbH (DE) 1986-04-02 EP disclosed
US-4134972-A OLIGOPEPTIDES HOFFMANN-LA ROCHE INC. (US) 1979-01-16 US disclosed
US-4127649-A PEPTIDES HOFFMANN-LA ROCHE INC. (US) 1978-11-28 US disclosed
US-4100275-A PEPTIDES HOFFMANN-LA ROCHE INC. (US) 1978-07-11 US disclosed