Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | AHR | P35869 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 7/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 10/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7162123 | 0.93 | ALDH1A1 (0.66) | ALDH1A1L3MBTL1AHRPOLBMEN1 | |
| SCHEMBL7161392 | 0.90 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1AHRPOLBMEN1 | |
| SCHEMBL6814926 | 0.82 | POLB (0.63) | ALDH1A1L3MBTL1AHRPOLBMEN1 | |
| SCHEMBL6815991 | 0.82 | SMN1; SMN2 (0.51) | ALDH1A1L3MBTL1AHRPOLBMEN1 | |
| SCHEMBL6816491 | 0.82 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1AHRPOLBMEN1 | |
| SCHEMBL7162646 | 0.81 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1AHRPOLBMEN1 | |
| SCHEMBL6815803 | 0.81 | GRM4 (0.54) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL7166846 | 0.80 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1AHRPOLBMEN1 | |
| SCHEMBL6815962 | 0.80 | SMN1; SMN2 (0.48) | ALDH1A1L3MBTL1AHRPOLBMEN1 | |
| SCHEMBL7166821 | 0.79 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1AHRPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6555561-B2 | N-(5-((((5-Chloro-2,4-dimethoxyphenyl)amino)thioxomethyl)-amino)-2 -pyridinyl)-2-methylbenzamide, for example; inhibiting replication of a herpes virus | WYETH | 2003-04-29 | — | — | US | disclosed |