Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7164667 | 0.83 | MEN1 (0.64) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6811008 | 0.82 | MAPT (0.61) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7162969 | 0.81 | MEN1 (0.78) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6814854 | 0.81 | LMNA (0.66) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7162179 | 0.80 | KMT2A (0.54) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6812064 | 0.80 | KDM4E (0.76) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7939055 | 0.80 | MAPT (0.70) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7165775 | 0.80 | MAPT (0.67) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6812142 | 0.80 | MAPT (0.67) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6815648 | 0.79 | MAPT (0.70) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6555561-B2 | N-(5-((((5-Chloro-2,4-dimethoxyphenyl)amino)thioxomethyl)-amino)-2 -pyridinyl)-2-methylbenzamide, for example; inhibiting replication of a herpes virus | WYETH | 2003-04-29 | — | — | US | disclosed |