SCHEMBL716485

SCHEMBL716485

Cc1c(F)cc(Br)c(F)c1F

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
KDM1A O60341 2/20 0.31
KDM1B Q8NB78 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15497511 0.84 HDAC1 (0.35) HDAC1HDAC6KDM1AKDM1B
SCHEMBL5734020 0.79 KDM1A (0.35) KDM1AKDM1B
SCHEMBL334330 0.79 KDM1A (0.31) HDAC1HDAC6KDM1AKDM1B
SCHEMBL4060447 0.79 KDM1A (0.31) HDAC1HDAC6KDM1AKDM1B
SCHEMBL28108065 0.78 HDAC1 (0.32) HDAC1HDAC6
SCHEMBL12689887 0.76 HDAC1 (0.37) HDAC1HDAC6KDM1AKDM1B
SCHEMBL172019 0.75 CA1 (0.35) HDAC1HDAC6
SCHEMBL1043011 0.75 CA12 (0.35) KDM1AKDM1B
SCHEMBL23813836 0.74 HDAC1 (0.35) HDAC1HDAC6KDM1AKDM1B
SCHEMBL3726607 0.74 CA1 (0.43) HDAC1HDAC6KDM1AKDM1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116813475-A Halogenated synthesis method of aromatic ring compound 北京大学 2023-09-29 CN claimed
CN-114957312-A Aryl silicon compound of conjugated olefin and preparation method and application thereof 南京工业大学 2022-08-30 CN claimed
CN-113831275-A Indole-substituted 6-phenylindenoindole derivative and preparation method and application thereof 上海兆维科技发展有限公司 2021-12-24 CN claimed
CN-111439737-B Vanadium-based sodium oxyfluorophosphate type sodium battery positive electrode material and preparation method thereof 西安交通大学 2021-11-30 CN claimed
CN-110590767-B Method for synthesizing AMG837 南方科技大学 2021-10-08 CN claimed
CN-113437291-A Lithium vanadium fluorophosphosilicate cathode material and preparation method thereof 西安交通大学 2021-09-24 CN claimed
CN-113321935-A High-corrosion-resistance silicone rubber material and preparation method thereof 深圳市泰科科技有限公司 2021-08-31 CN claimed
CN-111446449-B Multi-electron-transmission vanadium-based oxygen sodium fluophosphate battery material and preparation method thereof 西安交通大学 2021-07-09 CN claimed
CN-112354551-A Novel monoatomic metal photocatalyst, preparation method thereof and application thereof in carbon-oxygen cross-coupling reaction 中国科学院化学研究所 2021-02-12 CN claimed
CN-111439737-A Vanadium-based sodium oxyfluorophosphate type sodium battery positive electrode material and modified preparation method thereof 西安交通大学 2020-07-24 CN claimed
CN-111446449-A Multi-electron-transmission vanadium-based oxygen sodium fluophosphate battery material and preparation method thereof 西安交通大学 2020-07-24 CN claimed
CN-110590767-A Method for synthesizing AMG837 南方科技大学 2019-12-20 CN claimed
CN-120157620-A High-steric-hindrance dinaphthyl compound and application thereof in preparation of organic electroluminescent device 烟台显华科技集团股份有限公司 2025-06-17 CN disclosed
CN-119114163-B Noble metal-free photocatalyst and preparation method and application thereof 中山大学 2025-03-14 CN disclosed
CN-119114163-A Noble metal-free photocatalyst and preparation method and application thereof 中山大学 2024-12-13 CN disclosed
EP-3315502-B1 C,O-SPIRO ARYL GLYCOSIDE COMPOUNDS, PREPARATION THEREFOR AND USE THEREOF SHANGHAI INST MATERIA MEDICA CAS (CN) 2024-07-31 EP disclosed
US-5308541-A Electrooptic displays; broad nematic range; high clear point; chemical stability MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1994-05-03 US disclosed
US-5292454-A Trifluorotoluene compounds, and a liquid crystalline medium MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1994-03-08 US disclosed
US-4871469-A TRIFLUOROTOLUENE DERIVATIVES BESCRANKTER HAFTUNG (DE) 1989-10-03 US disclosed
US-3992536-A SEDATIVES AND MUSCLE RELAXANTS BOEHRINGER INGELHEIM GMBH (DT) 1976-11-16 US disclosed