Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.31 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15497511 | 0.84 | HDAC1 (0.35) | KDM1AKDM1BHDAC1HDAC6 | |
| SCHEMBL31026375 | 0.80 | TSHR (0.31) | KDM1AKDM1BHDAC1HDAC6CA12 | |
| SCHEMBL3730086 | 0.80 | CA1 (0.41) | KDM1AKDM1BHDAC1HDAC6CA12 | |
| SCHEMBL334330 | 0.79 | KDM1A (0.31) | KDM1AKDM1BHDAC1HDAC6CA12 | |
| SCHEMBL716485 | 0.79 | HDAC1 (0.35) | KDM1AKDM1BHDAC1HDAC6 | |
| SCHEMBL23304085 | 0.78 | CYP3A4 (0.33) | HDAC1HDAC6CA1CA2 | |
| SCHEMBL9876027 | 0.78 | POLB (0.30) | — | |
| SCHEMBL12689887 | 0.76 | HDAC1 (0.37) | KDM1AKDM1BHDAC1HDAC6 | |
| SCHEMBL31032207 | 0.75 | POLB (0.37) | — | |
| SCHEMBL22341925 | 0.75 | CA2 (0.39) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119285442-A | Method for synthesizing 2-methyl-3, 4, 5-trifluoro phenol | 石家庄市凯信电子材料有限公司 | 2025-01-10 | — | — | CN | claimed |
| CN-109761743-B | Preparation method of 2-methyl-3, 4, 5-trifluorobromobenzene | 浙江永太科技股份有限公司 | 2021-04-30 | — | — | CN | claimed |
| CN-109761743-A | The preparation method of 2- methyl -3,4,5- trifluorobromobenzene | 浙江永太科技股份有限公司 | 2019-05-17 | — | — | CN | claimed |
| CN-105967974-A | Preparation method of 2-methyl-3,4,5-trifluorobromobenzene | 蚌埠中实化学技术有限公司 | 2016-09-28 | — | — | CN | claimed |
| CN-119285442-A | Method for synthesizing 2-methyl-3, 4, 5-trifluoro phenol | 石家庄市凯信电子材料有限公司 | 2025-01-10 | — | — | CN | disclosed |
| CN-119285442-A | Method for synthesizing 2-methyl-3, 4, 5-trifluoro phenol | 石家庄市凯信电子材料有限公司 | 2025-01-10 | — | — | CN | disclosed |
| CN-109761743-B | Preparation method of 2-methyl-3, 4, 5-trifluorobromobenzene | 浙江永太科技股份有限公司 | 2021-04-30 | — | — | CN | disclosed |
| CN-109761743-B | Preparation method of 2-methyl-3, 4, 5-trifluorobromobenzene | 浙江永太科技股份有限公司 | 2021-04-30 | — | — | CN | disclosed |
| CN-109761743-B | Preparation method of 2-methyl-3, 4, 5-trifluorobromobenzene | 浙江永太科技股份有限公司 | 2021-04-30 | — | — | CN | disclosed |
| CN-109761743-A | The preparation method of 2- methyl -3,4,5- trifluorobromobenzene | 浙江永太科技股份有限公司 | 2019-05-17 | — | — | CN | disclosed |
| CN-109761743-A | The preparation method of 2- methyl -3,4,5- trifluorobromobenzene | 浙江永太科技股份有限公司 | 2019-05-17 | — | — | CN | disclosed |
| CN-105967974-B | A kind of preparation method of 2- methyl -3,4,5- trifluorobromobenzenes | 蚌埠中实化学技术有限公司 | 2018-08-31 | — | — | CN | disclosed |
| CN-105967974-B | A kind of preparation method of 2- methyl -3,4,5- trifluorobromobenzenes | 蚌埠中实化学技术有限公司 | 2018-08-31 | — | — | CN | disclosed |
| CN-105967974-A | Preparation method of 2-methyl-3,4,5-trifluorobromobenzene | 蚌埠中实化学技术有限公司 | 2016-09-28 | — | — | CN | disclosed |
| CN-105967974-A | Preparation method of 2-methyl-3,4,5-trifluorobromobenzene | 蚌埠中实化学技术有限公司 | 2016-09-28 | — | — | CN | disclosed |
| CN-105967974-A | Preparation method of 2-methyl-3,4,5-trifluorobromobenzene | 蚌埠中实化学技术有限公司 | 2016-09-28 | — | — | CN | disclosed |
| EP-2025669-A1 | Alpha-alkyl substituted N-acyltryptophanols | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-02-18 | — | — | EP | disclosed |
| US-20060178515-A1 | Tetrahydroisoquinolyl acetamide derivatives for use as orexin receptor antagonists | ACTELION PHARMACEUTICALS, LTD. (CH) | 2006-08-10 | — | — | US | disclosed |
| EP-1611104-A1 | TETRAHYDROISOQUINOLYL ACETAMIDE DERIVATIVES FOR USE AS OREXIN RECEPTOR ANTAGONISTS | Actelion Pharmaceuticals Ltd. (CH) | 2006-01-04 | — | — | EP | disclosed |
| WO-2004085403-A1 | TETRAHYDROISOQUINOLYL ACETAMIDE DERIVATIVES FOR USE AS OREXIN RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2004-10-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060178515-A1 | Tetrahydroisoquinolyl acetamide derivatives for use as orexin receptor antagonists | HCRTR2, HCRTR1, OXTR | KDM1A 1928/4885KDM1B 1771/4885HDAC1 737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.