Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.38 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.38 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.38 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.38 |
| ▸ | HK1 | P19367 | 1/20 | 0.37 |
| ▸ | HK2 | P52789 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | SLC5A2 | P31639 | 3/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9838031 | 1.00 | PTPN1 (0.38) | PTPN1LGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL13560566 | 0.80 | MAPK1 (0.41) | HK1HK2MAPK1MMP12SLC5A2 | |
| SCHEMBL564385 | 0.79 | MAPK1 (0.41) | LGALS9LGALS1LGALS3MAPK1 | |
| SCHEMBL11199589 | 0.79 | MAPK1 (0.41) | LGALS9LGALS1LGALS3MAPK1 | |
| SCHEMBL143296 | 0.79 | MAPK1 (0.41) | LGALS9LGALS1LGALS3MAPK1 | |
| SCHEMBL16026724 | 0.79 | MAPK1 (0.41) | LGALS9LGALS1LGALS3MAPK1 | |
| SCHEMBL8008210 | 0.77 | LGALS9 (0.41) | LGALS9LGALS1LGALS3LGALS7; LGALS7BHK1 | |
| SCHEMBL9094521 | 0.77 | LGALS9 (0.41) | LGALS9LGALS1LGALS3LGALS7; LGALS7BHK1 | |
| SCHEMBL16968411 | 0.77 | LGALS9 (0.41) | LGALS9LGALS1LGALS3LGALS7; LGALS7BHK1 | |
| SCHEMBL1131613 | 0.74 | SLC5A2 (0.47) | LGALS9LGALS1LGALS3LGALS7; LGALS7BSLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6548552-B1 | B-Mercaptoethanol antioxidant and surfactant; side effect reduction | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. | 2003-04-15 | — | — | US | disclosed |