Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 5/20 | 0.33 |
| ▸ | PGGT1B | P53609 | 5/20 | 0.33 |
| ▸ | FNTB | P49356 | 3/20 | 0.33 |
| ▸ | DNAJA1 | P31689 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | HTR5A | P47898 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6412093 | 0.75 | FNTA (0.35) | FNTAPGGT1BFNTBDNAJA1KCNH2 | |
| SCHEMBL6416010 | 0.75 | FNTA (0.33) | FNTAPGGT1BFNTBDNAJA1 | |
| SCHEMBL7165181 | 0.74 | FNTA (0.37) | FNTAPGGT1BFNTBDNAJA1 | |
| SCHEMBL7166236 | 0.74 | FNTA (0.37) | FNTAPGGT1BFNTBDNAJA1 | |
| SCHEMBL6475716 | 0.73 | FNTA (0.56) | FNTAPGGT1BFNTB | |
| SCHEMBL6411741 | 0.72 | FNTA (0.34) | FNTAPGGT1BFNTBDNAJA1HTR5A | |
| SCHEMBL1683543 | 0.72 | FNTA (0.53) | FNTAPGGT1BFNTB | |
| SCHEMBL7972250 | 0.72 | FNTA (0.53) | FNTAPGGT1BFNTB | |
| Water SCHEMBL7194386 | 0.72 | FNTA (0.53) | FNTAPGGT1BFNTB | |
| SCHEMBL7749673 | 0.72 | FNTA (0.53) | FNTAPGGT1BFNTBADRA1AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562823-B1 | Inhibition of farnesyl-protein transferase has been shown to block the growth of Ras-transformed cells in soft agar | MERCK & CO., INC. | 2003-05-13 | — | — | US | disclosed |