Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | BID | P55957 | 3/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.42 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28390493 | 0.91 | LIPG (0.53) | LIPGALOX5PTGS2BIDMCL1 | |
| SCHEMBL11136888 | 0.91 | LIPG (0.53) | LIPGALOX5PTGS2BIDMCL1 | |
| SCHEMBL27554686 | 0.88 | LIPG (0.43) | LIPGALOX5PTGS2BIDMCL1 | |
| SCHEMBL28983653 | 0.75 | LIPG (0.55) | LIPGALOX5PTGS2BIDMCL1 | |
| SCHEMBL5873329 | 0.74 | LIPG (0.58) | LIPGALOX5BIDMCL1PPARA | |
| SCHEMBL2803228 | 0.74 | LIPG (0.58) | LIPGALOX5BIDMCL1PPARA | |
| SCHEMBL28336811 | 0.74 | LIPG (0.58) | LIPGALOX5BIDMCL1PPARA | |
| SCHEMBL8384258 | 0.74 | LIPG (0.58) | LIPGALOX5BIDMCL1PPARA | |
| SCHEMBL11358479 | 0.74 | LIPG (0.58) | LIPGALOX5BIDMCL1PPARA | |
| SCHEMBL20656620 | 0.73 | LIPG (0.45) | LIPGALOX5NR1H2NR1H3CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6579997-B1 | Enhanced activity of metal complexes | UAB RESEARCH FOUNDATION | 2003-06-17 | — | — | US | disclosed |
| EP-1212134-A4 | METALLACROWN ETHER CATALYSTS FOR HYDROFORMYLATION | UAB RESEARCH FOUNDATION (US) | 2003-01-22 | — | — | EP | disclosed |
| EP-1212134-A1 | METALLACROWN ETHER CATALYSTS FOR HYDROFORMYLATION | UAB Research Foundation (US) | 2002-06-12 | — | — | EP | disclosed |
| WO-2001007156-A1 | METALLACROWN ETHER CATALYSTS FOR HYDROFORMYLATION | UAB RESEARCH FOUNDATION (US) | 2001-02-01 | — | — | WO | disclosed |