Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 15/20 | 0.43 |
| ▸ | FNTB | P49356 | 15/20 | 0.43 |
| ▸ | PGGT1B | P53609 | 11/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6417857 | 0.85 | HTR2A (0.42) | FNTAFNTBHTR2AHTR2CDRD4 | |
| SCHEMBL7721388 | 0.84 | FNTA (0.44) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL7721386 | 0.84 | FNTA (0.44) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL6409294 | 0.76 | FNTA (0.48) | FNTAFNTBPGGT1BHTR2ADRD4 | |
| SCHEMBL7168713 | 0.76 | FNTA (0.45) | FNTAFNTBPGGT1B | |
| SCHEMBL7164885 | 0.75 | HTR2A (0.38) | FNTAFNTBPGGT1BHTR2AHTR2C | |
| SCHEMBL6430353 | 0.74 | FNTA (0.48) | FNTAFNTBPGGT1B | |
| SCHEMBL7718625 | 0.73 | FNTA (0.60) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL7719418 | 0.73 | FNTA (0.60) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL7189205 | 0.70 | KCNH2 (0.44) | FNTAFNTBPGGT1BSIGMAR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562823-B1 | Inhibition of farnesyl-protein transferase has been shown to block the growth of Ras-transformed cells in soft agar | MERCK & CO., INC. | 2003-05-13 | — | — | US | disclosed |