Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 7/20 | 0.73 |
| ▸ | XDH | P47989 | 1/20 | 0.54 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | THRA | P10827 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5347661 | 0.89 | PTPN11 (0.57) | PTPN11XDHPLA2G4BNPC1RAB9A | |
| SCHEMBL27245989 | 0.85 | PTPN11 (1.00) | PTPN11LMNAMAPTMEN1KMT2A | |
| SCHEMBL6421561 | 0.85 | PTPN11 (0.55) | PTPN11XDHPLA2G4BNPC1RAB9A | |
| SCHEMBL8922483 | 0.85 | PTPN11 (0.55) | PTPN11XDHPLA2G4BNPC1RAB9A | |
| SCHEMBL3195027 | 0.85 | PTPN11 (0.55) | PTPN11XDHPLA2G4BNPC1RAB9A | |
| SCHEMBL9626821 | 0.82 | PTPN11 (0.68) | PTPN11XDHPLA2G4BALDH1A1THRA | |
| SCHEMBL9626727 | 0.82 | PTPN11 (0.68) | PTPN11XDHPLA2G4BALDH1A1THRA | |
| SCHEMBL9627241 | 0.82 | PTPN11 (0.68) | PTPN11XDHPLA2G4BALDH1A1THRA | |
| SCHEMBL7170404 | 0.82 | PTPN11 (0.80) | PTPN11ALDH1A1LMNAMAPTTHRA | |
| SCHEMBL5343331 | 0.82 | PTPN11 (0.68) | PTPN11XDHPLA2G4BALDH1A1THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6569504-B1 | Dimers of LC-like compounds in which the monomers are linked to each other through a high birefringence moiety (dimerization linker) | DISPLAYTECH, INC. | 2003-05-27 | — | — | US | disclosed |
| US-6139771-A | USEFUL IN ELECTOOPTICAL AND NON-LINEAR OPTICAL APPLICATIONS | DISPLAYTECH, INC. (US) | 2000-10-31 | — | — | US | disclosed |