Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 2/20 | 0.68 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.66 |
| ▸ | THRA | P10827 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | RARB | P10826 | 3/20 | 0.59 |
| ▸ | XDH | P47989 | 1/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.54 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9626821 | 1.00 | PTPN11 (0.68) | PTPN11PLA2G4BTHRATHRBRARB | |
| SCHEMBL8176761 | 1.00 | PTPN11 (0.68) | PTPN11PLA2G4BTHRATHRBRARB | |
| SCHEMBL5343331 | 1.00 | PTPN11 (0.68) | PTPN11PLA2G4BTHRATHRBRARB | |
| SCHEMBL9627241 | 1.00 | PTPN11 (0.68) | PTPN11PLA2G4BTHRATHRBRARB | |
| SCHEMBL5348288 | 0.91 | XDH (0.55) | PTPN11PLA2G4BTHRATHRBXDH | |
| SCHEMBL12431954 | 0.91 | PLA2G4B (0.77) | PTPN11PLA2G4BTHRATHRBPRSS1 | |
| SCHEMBL7696499 | 0.91 | PLA2G4B (0.77) | PTPN11PLA2G4BTHRATHRBPRSS1 | |
| SCHEMBL9626808 | 0.91 | PLA2G4B (0.77) | PTPN11PLA2G4BTHRATHRBPRSS1 | |
| Hydrochloric Acid SCHEMBL9627735 | 0.90 | PLA2G4B (0.75) | PTPN11PLA2G4BTHRATHRBPRSS1 | |
| SCHEMBL27403163 | 0.90 | PLA2G4B (0.74) | PTPN11PLA2G4BTHRATHRBPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0188222-B1 | NOVEL LIQUID CRISTALLINE COMPOUNDS HAVING SUBSTITUENTS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1992-04-29 | — | — | EP | disclosed |
| US-4943386-A | FERROELECTRIC, GOOD RESPONSE AND MEMORY | DAINIPPON INK & CHEMICALS, INC. (JP) | 1990-07-24 | — | — | US | disclosed |
| US-4828754-A | TILT-TYPE CHIRAL SMECTIC PHASE | DAINIPPON INK & CHEMICALS, INC. (JP) | 1989-05-09 | — | — | US | disclosed |
| EP-0188222-A2 | Novel liquid cristalline compounds having substituents | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1986-07-23 | — | — | EP | disclosed |