Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.36 |
| ▸ | CBFB | Q13951 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 6/20 | 0.36 |
| ▸ | KDR | P35968 | 6/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8504632 | 0.68 | CYP3A4 (0.61) | CYP3A4TSHRRECQLRIPK2KDM4E | |
| Methoxymethane SCHEMBL9765146 | 0.67 | MAOB (0.47) | CYP3A4TSHRRECQLKDM4EALDH1A1 | |
| SCHEMBL27314734 | 0.65 | RAPGEF4 (0.54) | CYP3A4TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL4257297 | 0.65 | — | — | |
| SCHEMBL31129158 | 0.65 | — | — | |
| Phenol SCHEMBL28238632 | 0.64 | TSHR (0.83) | CYP3A4TSHRRECQLRIPK2KDM4E | |
| SCHEMBL18466888 | 0.64 | CYP3A4 (0.47) | CYP3A4TSHRRECQLRIPK2KDM4E | |
| SCHEMBL126869 | 0.63 | TSHR (1.00) | CYP3A4TSHRRECQLRIPK2KDM4E | |
| SCHEMBL4286209 | 0.63 | TSHR (0.55) | CYP3A4TSHRRECQLRIPK2ALDH1A1 | |
| SCHEMBL13577700 | 0.63 | HDAC6 (0.68) | CYP3A4TSHRKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562080-B2 | 2-arylaminomethyl-4-aminophenols; light fastness, fastness to shampooing, fastness to permanent wave treatment | CLAIROL INCORPORATED | 2003-05-13 | — | — | US | disclosed |
| US-20020144355-A1 | Primary intermediates for oxidative coloration of hair | WELLA OPERATIONS US, LLC | 2002-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020144355-A1 | Primary intermediates for oxidative coloration of hair | CYC1, CBR1, CBR3 | CYP3A4 91/4885TSHR 2471/4885RECQL 1927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.