Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 20/20 | 0.59 |
| ▸ | PGGT1B | P53609 | 20/20 | 0.59 |
| ▸ | FNTB | P49356 | 19/20 | 0.59 |
| ▸ | KRAS | P01116 | 1/20 | 0.52 |
| ▸ | DNAJA1 | P31689 | 1/20 | 0.52 |
| ▸ | RAP1A | P62834 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7163110 | 0.88 | FNTA (0.63) | FNTAPGGT1BFNTBKRASDNAJA1 | |
| SCHEMBL7167085 | 0.86 | FNTA (0.61) | FNTAPGGT1BFNTBKRASDNAJA1 | |
| SCHEMBL7168708 | 0.85 | FNTA (0.65) | FNTAPGGT1BFNTBKRASDNAJA1 | |
| SCHEMBL7167927 | 0.83 | FNTA (0.76) | FNTAPGGT1BFNTBKRASDNAJA1 | |
| SCHEMBL7164587 | 0.83 | FNTA (0.75) | FNTAPGGT1BFNTBKRASDNAJA1 | |
| SCHEMBL7166233 | 0.81 | FNTA (0.61) | FNTAPGGT1BFNTBKRASDNAJA1 | |
| SCHEMBL7163163 | 0.80 | FNTA (0.59) | FNTAPGGT1BFNTBKRASDNAJA1 | |
| SCHEMBL7159363 | 0.80 | FNTA (0.59) | FNTAPGGT1BFNTBKRASDNAJA1 | |
| SCHEMBL7163235 | 0.80 | FNTA (0.60) | FNTAPGGT1BFNTBKRASDNAJA1 | |
| SCHEMBL7168707 | 0.80 | FNTA (0.60) | FNTAPGGT1BFNTBKRASDNAJA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562823-B1 | Inhibition of farnesyl-protein transferase has been shown to block the growth of Ras-transformed cells in soft agar | MERCK & CO., INC. | 2003-05-13 | — | — | US | claimed |
| US-6562823-B1 | Inhibition of farnesyl-protein transferase has been shown to block the growth of Ras-transformed cells in soft agar | MERCK & CO., INC. | 2003-05-13 | — | — | US | disclosed |