SCHEMBL7166285

SCHEMBL7166285

CCOP(=O)(OCC)C(Cl)=Cc1cc(-n2nc3n(c2=O)CCCC3)c(F)cc1Cl

nearest known ligand 0.47

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 20/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7892882 0.78 PPOX (0.40)
SCHEMBL7162971 0.78 PPOX (0.40)
SCHEMBL9664791 0.75 DHODH (0.51) DHODH
SCHEMBL10386333 0.75 DHODH (0.50) DHODH
SCHEMBL9665722 0.73 DHODH (0.51) DHODH
SCHEMBL4072262 0.72 DHODH (0.54) DHODH
SCHEMBL10386332 0.72 DHODH (0.47) DHODH
SCHEMBL9664832 0.72 DHODH (0.47) DHODH
SCHEMBL10824421 0.72 DHODH (0.54) DHODH
SCHEMBL4390450 0.71 DHODH (0.51) DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0879239-B1 SUBSTITUTED AROMATIC PHOSPHONIC ACID DERIVATIVES BASF AG (DE) 2003-04-23 EP disclosed
US-6175007-B1 HERBICIDES AND DEFOLIANTS BASF AKTIENGESELLSCHAFT (DE) 2001-01-16 US disclosed
EP-0879239-A1 SUBSTITUTED AROMATIC PHOSPHONIC ACID DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 1998-11-25 EP disclosed