Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 7/20 | 0.42 |
| ▸ | NOS1 | P29475 | 5/20 | 0.34 |
| ▸ | PNP | P00491 | 3/20 | 0.33 |
| ▸ | PAH | P00439 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9615455 | 1.00 | HPRT1 (0.42) | HPRT1NOS1PNPPAHNOS3 | |
| SCHEMBL598708 | 1.00 | HPRT1 (0.42) | HPRT1NOS1PNPPAHNOS3 | |
| SCHEMBL9309980 | 0.89 | HPRT1 (0.41) | HPRT1NOS1PNPPAHNOS3 | |
| SCHEMBL9309770 | 0.89 | HPRT1 (0.41) | HPRT1NOS1PNPPAHNOS3 | |
| SCHEMBL9309119 | 0.88 | HPRT1 (0.42) | HPRT1NOS1PNPPAHNOS3 | |
| SCHEMBL9020140 | 0.88 | HPRT1 (0.42) | HPRT1NOS1PNPPAH | |
| SCHEMBL9309013 | 0.88 | HPRT1 (0.42) | HPRT1NOS1PNPPAHNOS3 | |
| SCHEMBL9020214 | 0.87 | HPRT1 (0.39) | HPRT1NOS1PAH | |
| SCHEMBL9020524 | 0.86 | HPRT1 (0.38) | HPRT1NOS1PNPPAH | |
| SCHEMBL9706279 | 0.84 | HPRT1 (0.41) | HPRT1NOS1PAHNOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9290533-B2 | β-L-2′-deoxy-nucleosides for the treatment of hepatitis B | NOVARTIS AG (CH) | 2016-03-22 | — | — | US | claimed |
| US-6566344-B1 | Administering beta-L-2'-deoxycytidine compound for therapy of hepatitis B virus infection | IDENIX PHARMACEUTICALS, INC. | 2003-05-20 | — | — | US | claimed |
| EP-0477871-A2 | Antiviral composition, containing guanine derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1992-04-01 | — | — | EP | claimed |
| JP-8127536-A | — | — | None | — | — | JP | disclosed |
| JP-9301869-A | — | — | None | — | — | JP | disclosed |
| JP-H09301869-A | PERCUTANEOUS ABSORPTION COMPOSITION | NIPPON KAYAKU CO LTD | 1997-11-25 | — | — | JP | disclosed |
| CN-1157563-A | Ointment formulation | NIPPON KAYAKU KK (JP) | 1997-08-20 | — | — | CN | disclosed |
| JP-H08127536-A | OINTMENT | NIPPON KAYAKU CO LTD | 1996-05-21 | — | — | JP | disclosed |
| EP-0458312-B1 | Novel cyclobutane derivatives | NIPPON KAYAKU KK (JP) | 1996-03-20 | — | — | EP | disclosed |
| US-5324730-A | Viricides | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1994-06-28 | — | — | US | disclosed |
| EP-0477871-A2 | Antiviral composition, containing guanine derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1992-04-01 | — | — | EP | disclosed |
| EP-0477871-A2 | Antiviral composition, containing guanine derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1992-04-01 | — | — | EP | disclosed |
| EP-0458312-A1 | Novel cyclobutane derivatives | Nippon Kayaku Kabushiki Kaisha (JP) | 1991-11-27 | — | — | EP | disclosed |