Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 8/20 | 0.41 |
| ▸ | NOS1 | P29475 | 5/20 | 0.33 |
| ▸ | PNP | P00491 | 2/20 | 0.33 |
| ▸ | PAH | P00439 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9309980 | 1.00 | HPRT1 (0.41) | HPRT1NOS1PNPPAHNOS3 | |
| SCHEMBL598708 | 0.89 | HPRT1 (0.42) | HPRT1NOS1PNPPAHNOS3 | |
| SCHEMBL9615455 | 0.89 | HPRT1 (0.42) | HPRT1NOS1PNPPAHNOS3 | |
| SCHEMBL7166497 | 0.89 | HPRT1 (0.42) | HPRT1NOS1PNPPAHNOS3 | |
| SCHEMBL9310753 | 0.83 | HPRT1 (0.46) | HPRT1NOS1PAHNOS3NOS2 | |
| SCHEMBL9309013 | 0.82 | HPRT1 (0.42) | HPRT1NOS1PNPPAHNOS3 | |
| SCHEMBL9020140 | 0.82 | HPRT1 (0.42) | HPRT1NOS1PNPPAH | |
| SCHEMBL9309119 | 0.82 | HPRT1 (0.42) | HPRT1NOS1PNPPAHNOS3 | |
| SCHEMBL9308669 | 0.81 | HPRT1 (0.41) | HPRT1NOS1PNPNOS3NOS2 | |
| SCHEMBL9309722 | 0.81 | HPRT1 (0.41) | HPRT1NOS1PNPNOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374625-A | Bis/hydroxymethyl/cycloalkyl derivatives; viricides | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1994-12-20 | — | — | US | disclosed |