Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 11/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 11/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ABAT | P80404 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18400030 | 0.87 | TAAR1 (0.50) | TAAR1SLC6A2ESR1ESR2TRPV1 | |
| SCHEMBL8595139 | 0.87 | TAAR1 (0.50) | TAAR1SLC6A2ESR1ESR2TRPV1 | |
| SCHEMBL22467712 | 0.85 | TAAR1 (0.48) | TAAR1SLC6A2ESR1ESR2TRPV1 | |
| SCHEMBL22077715 | 0.85 | TAAR1 (0.48) | TAAR1SLC6A2ESR1ESR2TRPV1 | |
| SCHEMBL106892 | 0.85 | ESR1 (0.59) | TAAR1SLC6A2ESR1ESR2TRPV1 | |
| SCHEMBL27882228 | 0.85 | TAAR1 (0.48) | TAAR1SLC6A2ESR1ESR2TRPV1 | |
| SCHEMBL28484973 | 0.84 | TAAR1 (0.52) | TAAR1SLC6A2ESR1ESR2TRPV1 | |
| SCHEMBL452092 | 0.84 | ESR1 (0.54) | TAAR1SLC6A2ESR1ESR2TRPV1 | |
| SCHEMBL450874 | 0.83 | TAAR1 (0.56) | TAAR1SLC6A2ESR1ESR2SLC7A5 | |
| SCHEMBL15928032 | 0.83 | TAAR1 (0.56) | TAAR1SLC6A2ESR1ESR2SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6617313-B1 | 2,6-dihydroxy-2-(P-hydroxybenzyl)-3(2H)benzofuran-7-C-beta -D-glucopyranoside, obtained by solvent extraction of powdered hardwood of Pterocarpus marsupium; treatment of diabetes | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-09-09 | — | — | US | disclosed |
| US-6562791-B1 | Isolated from Pterocarpus marsupium and to a process for the isolation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-05-13 | — | — | US | disclosed |