SCHEMBL452092

SCHEMBL452092

Oc1ccc(CCC(O)Cc2ccc(O)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.54
ESR2 Q92731 4/20 0.54
TRPV1 Q8NER1 1/20 0.51
DPP4 P27487 1/20 0.49
CA2 P00918 1/20 0.48
TAAR1 Q96RJ0 4/20 0.47
SLC6A2 P23975 2/20 0.47
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
HTR1A P08908 1/20 0.46
ADRA2A P08913 1/20 0.46
CYP2C19 P33261 1/20 0.46
HTR3A P46098 1/20 0.46
BACE1 P56817 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
BLM P54132 1/20 0.45
KMT2A Q03164 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
LTA4H P09960 1/20 0.45
ADRB2 P07550 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL145170 0.92 TRPV1 (0.62) TRPV1DPP4SLC6A2KDM4EHTR1A
SCHEMBL7270279 0.89 ESR1 (0.62) ESR1ESR2TRPV1DPP4CA2
(+)-Hannokinol SCHEMBL30361499 0.84 ESR1 (0.56) ESR1ESR2TRPV1DPP4CA2
(+)-Hannokinol SCHEMBL23229864 0.84 ESR1 (0.56) ESR1ESR2TRPV1DPP4CA2
(+)-Hannokinol SCHEMBL31237222 0.84 ESR1 (0.56) ESR1ESR2TRPV1DPP4CA2
SCHEMBL7166607 0.84 TAAR1 (0.56) ESR1ESR2TRPV1TAAR1SLC6A2
SCHEMBL11753264 0.83 ESR1 (0.54) ESR1ESR2TRPV1DPP4CA2
SCHEMBL28484973 0.83 TAAR1 (0.52) ESR1ESR2TRPV1CA2TAAR1
SCHEMBL14402690 0.81 ESR1 (0.61) ESR1ESR2TRPV1TAAR1SLC6A2
SCHEMBL28402648 0.81 TAAR1 (0.45) ESR1ESR2TRPV1TAAR1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2463374-A2 Isolated alcohol dehydrogenase enzymes and uses thereof Bio Architecture Lab, Inc. (US) 2012-06-13 EP claimed
US-20090155873-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-18 US claimed
US-20090139134-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-04 US claimed
EP-3230463-B2 RAPID PRETREATMENT APALTA PATENTS OUE (EE) 2025-07-16 EP disclosed
US-20240425893-A1 RAPID PRETREATMENT Apalta Patents OÜ (EE) 2024-12-26 US disclosed
US-12054761-B2 Rapid pretreatment Apalta Patents OÜ (EE) 2024-08-06 US disclosed
US-11821047-B2 High pressure zone formation for pretreatment Apalta Patent OÜ (EE) 2023-11-21 US disclosed
US-20230295678-A1 RAPID PRETREATMENT Apalta Patents OÜ (EE) 2023-09-21 US disclosed
EP-4098750-A1 RAPID PRETREATMENT Sweetwater Energy, Inc. (US) 2022-12-07 EP disclosed
EP-3230463-B1 RAPID PRETREATMENT SWEETWATER ENERGY INC (US) 2022-05-25 EP disclosed
US-11332723-B2 Engineered microorganisms for production of commodity chemicals and cellular biomass THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-05-17 US disclosed
WO-2011088422-A2 BIOFUEL PRODUCTION USING BIOFILM IN FERMENTATION QTEROS, INC. (US) 2011-07-21 WO disclosed
WO-2011072264-A2 METHODS AND COMPOSITIONS FOR BIOMASS TREATMENT QTEROS, INC. (US) 2011-06-16 WO disclosed
US-20100298611-A1 PRODUCTION OF FERMENTIVE END PRODUCTSFROM CLOSTRIDIUM sp. QTEROS, INC. (US) 2010-11-25 US disclosed
US-20100279354-A1 ADAPTING MICROORGANISMS FOR AGRICULTURAL PRODUCTS EVOLUGATE, LLC (US) 2010-11-04 US disclosed
US-20100268000-A1 Compositions and Methods for Fermentation of Biomass QTEROS, INC. (US) 2010-10-21 US disclosed
US-20100086981-A1 COMPOSITIONS AND METHODS FOR IMPROVED SACCHARIFICATION OF BIOMASS QTEROS, INC. (US) 2010-04-08 US disclosed
US-20090203089-A1 ISOLATED ALCOHOL DEHYDROGENASE ENZYMES AND USES THEREOF BIO ARCHITECTURE LAB, INC. (US) 2009-08-13 US disclosed
US-20090155873-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-18 US disclosed
US-20090139134-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090139134-A1 BIOFUEL PRODUCTION MGAM, DCXR, MANBA ESR1 3581/4885ESR2 3683/4885TRPV1 3969/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.