SCHEMBL716692

SCHEMBL716692

C=C(C)C(=O)OCCCCCCN

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.69
POLB P06746 1/20 0.51
APEX1 P27695 1/20 0.51
HTT P42858 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
THRB P10828 2/20 0.50
PAOX Q6QHF9 3/20 0.43
ALDH1A1 P00352 5/20 0.39
CYP3A4 P08684 1/20 0.38
HTR2C P28335 1/20 0.36
MEN1 O00255 1/20 0.35
PLG P00747 1/20 0.35
LMNA P02545 1/20 0.35
ALOX15 P16050 1/20 0.35
SLC6A2 P23975 1/20 0.35
RECQL P46063 1/20 0.35
SLC6A3 Q01959 1/20 0.35
KMT2A Q03164 1/20 0.35
NAAA Q02083 1/20 0.35
CYP1A2 P05177 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL718223 1.00 TSHR (0.69) TSHRPOLBAPEX1HTTTDP1
SCHEMBL1562267 1.00 TSHR (0.69) TSHRPOLBAPEX1HTTTDP1
SCHEMBL112966 1.00 TSHR (0.69) TSHRPOLBAPEX1HTTTDP1
SCHEMBL12200709 1.00 TSHR (0.69) TSHRPOLBAPEX1HTTTDP1
SCHEMBL9586892 1.00 TSHR (0.69) TSHRPOLBAPEX1HTTTDP1
SCHEMBL31616810 1.00 TSHR (0.69) TSHRPOLBAPEX1HTTTDP1
SCHEMBL14097216 1.00 TSHR (0.69) TSHRPOLBAPEX1HTTTDP1
SCHEMBL1562176 1.00 TSHR (0.69) TSHRPOLBAPEX1HTTTDP1
SCHEMBL9331676 1.00 TSHR (0.69) TSHRPOLBAPEX1HTTTDP1
Hydrochloric Acid SCHEMBL11438451 0.98 TSHR (0.67) TSHRPOLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250009416-A1 COMBINATION TUMOR TREATMENT BOSTON SCIENTIFIC SCIMED, INC. (US) 2025-01-09 US claimed
EP-4121006-A1 COMBINATION TUMOR TREATMENT Boston Scientific Scimed Inc. (US) 2023-01-25 EP claimed
CN-115427018-A Combination therapy for tumors 波士顿科学国际有限公司 2022-12-02 CN claimed
US-11382929-B2 Compositions and methods to treat disease REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2022-07-12 US claimed
WO-2021188630-A1 COMBINATION TUMOR TREATMENT BOSTON SCIENTIFIC SCIMED, INC. (US) 2021-09-23 WO claimed
US-20200405746-A1 COMPOSITIONS AND METHODS TO TREAT DISEASE REGENTS OF THE UNIVERSITY OF MINNESOTA 2020-12-31 US claimed
US-20080004402-A1 Polymeric product for film formation BORBELY JANOS 2008-01-03 US claimed
EP-1201720-B1 Printing fluid additives promoting overcoat adhesion HEWLETT PACKARD CO (US) 2004-09-15 EP claimed
US-6610412-B2 Clear protective thermal transfer overcoating and acrylic polymer compatibilizer; computer prints HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2003-08-26 US claimed
US-20030119973-A1 Printing fluid additives promoting overcoat adhesion HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2003-06-26 US claimed
US-6417249-B1 INK JET PRINTING INK FOR COLOR VEHICLES, CORE/SHELL BINDERS, SMUDGE PROOF HEWLETT-PACKARD COMPANY 2002-07-09 US claimed
EP-1201720-A1 Printing fluid additives promoting overcoat adhesion Hewlett-Packard Company (US) 2002-05-02 EP claimed
US-6248805-B1 THERMAL INK JET PRNTING HEWLETT-PACKARD COMPANY 2001-06-19 US claimed
US-6165988-A Medicament in particulate form Noe, Christian (AT) 2000-12-26 US claimed
US-6057384-A VEHICLE AND COLORANT ASSOCIATED WITH A PRIMER CORE/SHELL POLYMER; DURABLR SMEAR-FAST FILM HEWLETT-PACKARD COMPANY (US) 2000-05-02 US claimed
US-5990202-A DURABLE, SMEAR-FAST INK FILMS COMPRISING DUAL ENCAPSULATED COLORANT; A PRIMER CORE/SHELL POLYMER COATING A COLORANT (ADHESION) AND AN EXTERIOR CORE/SHELL POLYMER COATING FOR DURABILITY HEWLETT-PACKARD COMPANY (US) 1999-11-23 US claimed
US-5213934-A Core of colorant and binder grafted to polymeric shell XEROX CORPORATION (US) 1993-05-25 US claimed
US-12504686-B2 Black light-shielding photosensitive resin composition, black matrix, black light-shielding film, frame and filling material for splicing area ECHEM SOLUTIONS CORP. (TW) 2025-12-23 US disclosed
US-5213934-A Core of colorant and binder grafted to polymeric shell XEROX CORPORATION (US) 1993-05-25 US disclosed
US-4968559-A RELEASING BANDO CHEMICAL INDUSTRIES. LTD. (JP) 1990-11-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11382929-B2 Compositions and methods to treat disease SGMS1, SGMS2, LIPA TSHR 4631/4885POLB 2201/4885APEX1 639/4885
US-20200405746-A1 COMPOSITIONS AND METHODS TO TREAT DISEASE SGMS1, SGMS2, LIPA TSHR 4631/4885POLB 2201/4885APEX1 639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.