Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.62 |
| ▸ | BCHE | P06276 | 1/20 | 0.62 |
| ▸ | ACHE | P22303 | 1/20 | 0.62 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | PDE4A | P27815 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 3/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 3/20 | 0.56 |
| ▸ | CA4 | P22748 | 3/20 | 0.56 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.53 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4908720 | 1.00 | APP (0.62) | APPBCHEACHETRPV1CHRM1 | |
| Hydrochloric Acid SCHEMBL4419816 | 0.99 | APP (0.61) | APPBCHEACHETRPV1CHRM1 | |
| Hydrochloric Acid SCHEMBL4909193 | 0.99 | APP (0.61) | APPBCHEACHETRPV1CHRM1 | |
| SCHEMBL4431747 | 0.96 | APP (0.63) | APPBCHEACHETRPV1CHRM1 | |
| SCHEMBL3817985 | 0.96 | APP (0.63) | APPBCHEACHETRPV1CHRM1 | |
| Hydrochloric Acid SCHEMBL4743234 | 0.95 | APP (0.62) | APPBCHEACHETRPV1CHRM1 | |
| Hydrochloric Acid SCHEMBL4421826 | 0.95 | APP (0.62) | APPBCHEACHETRPV1CHRM1 | |
| Hydrochloric Acid SCHEMBL4743230 | 0.95 | APP (0.62) | APPBCHEACHETRPV1CHRM1 | |
| SCHEMBL3820586 | 0.91 | CHRM1 (0.61) | APPBCHEACHETRPV1CHRM1 | |
| SCHEMBL4431787 | 0.91 | CHRM1 (0.61) | APPBCHEACHETRPV1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1538951-B | Omega-aminoalkylamides of R-2-aryl-propionic acids as inhibitors of chemotaxis of polymorphonucleate and mononucleate cells | DOMPE SPA | 2013-08-28 | — | — | CN | claimed |
| EP-1366018-A1 | OMEGA-AMINOALKYLAMIDES OF R-2-ARYL-PROPIONIC ACIDS AS INHIBITORS OF THE CHEMOTAXIS OF POLYMORPHONUCLEATE AND MONONUCLEATE CELLS | Dompé S.P.A. (IT) | 2003-12-03 | — | — | EP | disclosed |
| WO-2002068377-A1 | OMEGA-AMINOALKYLAMIDES OF R-2-ARYL-PROPIONIC ACIDS AS INHIBITORS OF THE CHEMOTAXIS OF POLYMORPHONUCLEATE AND MONONUCLEATE CELLS | Dompé S.p.A. (IT) | 2002-09-06 | — | — | WO | disclosed |