Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.63 |
| ▸ | BCHE | P06276 | 1/20 | 0.63 |
| ▸ | ACHE | P22303 | 1/20 | 0.63 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.58 |
| ▸ | PDE4A | P27815 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 3/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 3/20 | 0.56 |
| ▸ | CA4 | P22748 | 3/20 | 0.56 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.55 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4431747 | 1.00 | APP (0.63) | APPBCHEACHETRPV1CHRM1 | |
| Hydrochloric Acid SCHEMBL4421826 | 0.99 | APP (0.62) | APPBCHEACHETRPV1CHRM1 | |
| Hydrochloric Acid SCHEMBL4743234 | 0.99 | APP (0.62) | APPBCHEACHETRPV1CHRM1 | |
| Hydrochloric Acid SCHEMBL4743230 | 0.99 | APP (0.62) | APPBCHEACHETRPV1CHRM1 | |
| SCHEMBL7167066 | 0.96 | APP (0.62) | APPBCHEACHETRPV1CHRM1 | |
| SCHEMBL4908720 | 0.96 | APP (0.62) | APPBCHEACHETRPV1CHRM1 | |
| Hydrochloric Acid SCHEMBL4909193 | 0.95 | APP (0.61) | APPBCHEACHETRPV1CHRM1 | |
| Hydrochloric Acid SCHEMBL4419816 | 0.95 | APP (0.61) | APPBCHEACHETRPV1CHRM1 | |
| SCHEMBL4431787 | 0.92 | CHRM1 (0.61) | APPBCHEACHETRPV1CHRM1 | |
| SCHEMBL3820586 | 0.92 | CHRM1 (0.61) | APPBCHEACHETRPV1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3210964-A1 | POSITIVELY CHARGED WATER-SOLUBLE PRODRUGS OF IBUPROFEN WITH VERY FAST SKIN PENETRATION RATE | Techfields Biochem Co. Ltd (CN) | 2017-08-30 | — | — | EP | claimed |
| EP-1366018-B1 | OMEGA-AMINOALKYLAMIDES OF (R)-2-ARYL-PROPIONIC ACIDS AS INHIBITORS OF THE CHEMOTAXIS OF POLYMORPHONUCLEATE AND MONONUCLEATE CELLS | DOMPÉ FARMACEUTICI S P A (IT) | 2016-07-06 | — | — | EP | claimed |
| CN-1538951-B | Omega-aminoalkylamides of R-2-aryl-propionic acids as inhibitors of chemotaxis of polymorphonucleate and mononucleate cells | DOMPE SPA | 2013-08-28 | — | — | CN | claimed |
| US-20090238763-A1 | HIGH PENETRATION COMPOSITIONS AND USES THEREOF | TECHFIELDS PHARMA CO., LTD. (CN) | 2009-09-24 | — | — | US | claimed |
| CN-1538951-A | Omega-aminoalkylamides of R-2-aryl-propionic acids as inhibitors of chemotaxis of polymorphonucleate and mononucleate cells | ��ķ�ɷ�����˾ | 2004-10-20 | — | — | CN | claimed |
| CN-1538951-B | Omega-aminoalkylamides of R-2-aryl-propionic acids as inhibitors of chemotaxis of polymorphonucleate and mononucleate cells | DOMPE SPA | 2013-08-28 | — | — | CN | disclosed |
| CN-1538951-A | Omega-aminoalkylamides of R-2-aryl-propionic acids as inhibitors of chemotaxis of polymorphonucleate and mononucleate cells | ��ķ�ɷ�����˾ | 2004-10-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090238763-A1 | HIGH PENETRATION COMPOSITIONS AND USES THEREOF | HPGDS, PTGIS, PTGES | APP 1270/4885BCHE 1180/4885ACHE 2313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.