Phthalic Acid

Phthalic Acid

SCHEMBL7167306

N.O=C(O)c1ccccc1C(=O)O.O=C(O)c1ccccc1C(=O)O

nearest known ligand 0.93

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.93
ALOX15 P16050 1/20 0.93
AKR1C3 P42330 3/20 0.67
NAPRT Q6XQN6 2/20 0.65
KDM4E B2RXH2 1/20 0.65
CA12 O43570 1/20 0.65
CA1 P00915 1/20 0.65
CA2 P00918 1/20 0.65
HMGB1 P09429 1/20 0.65
HPGD P15428 1/20 0.65
CA4 P22748 1/20 0.65
CA6 P23280 1/20 0.65
CA7 P43166 1/20 0.65
SMN1; SMN2 Q16637 1/20 0.65
CA9 Q16790 1/20 0.65
CA14 Q9ULX7 1/20 0.65
MAPT P10636 2/20 0.62
HDAC8 Q9BY41 1/20 0.62
POLB P06746 1/20 0.59
NR4A1 P22736 3/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL533819 1.00 ALDH1A1 (0.93) ALDH1A1ALOX15AKR1C3NAPRTKDM4E
Phthalic Acid SCHEMBL533818 1.00 ALDH1A1 (0.93) ALDH1A1ALOX15AKR1C3NAPRTKDM4E
Phthalic Acid SCHEMBL234376 1.00 ALDH1A1 (0.93) ALDH1A1ALOX15AKR1C3NAPRTKDM4E
Phthalic Acid SCHEMBL28266179 0.97 ALDH1A1 (0.88) ALDH1A1ALOX15AKR1C3NAPRTKDM4E
Phthalic Acid SCHEMBL28132941 0.97 ALDH1A1 (0.88) ALDH1A1ALOX15AKR1C3NAPRTKDM4E
Phthalic Acid SCHEMBL29037477 0.97 ALDH1A1 (0.88) ALDH1A1ALOX15AKR1C3NAPRTKDM4E
Phthalic Acid SCHEMBL29037475 0.97 ALDH1A1 (0.88) ALDH1A1ALOX15AKR1C3NAPRTKDM4E
Phthalic Acid SCHEMBL146125 0.97 ALDH1A1 (1.00) ALDH1A1ALOX15AKR1C3NAPRTKDM4E
Phthalic Acid SCHEMBL1686043 0.97 ALDH1A1 (1.00) ALDH1A1ALOX15AKR1C3NAPRTKDM4E
Phthalic Acid SCHEMBL4452470 0.97 ALDH1A1 (1.00) ALDH1A1ALOX15AKR1C3NAPRTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0924097-B1 Outermost layers for use in thermographic recording material AGFA GEVAERT (BE) 2003-04-09 EP disclosed
EP-0924098-B1 Outermost layers for use in thermographic recording materials AGFA GEVAERT (BE) 2002-05-29 EP disclosed
US-6127313-A THERMOGRAPHIC RECORDING MATERIAL COMPRISING ON THE SAME SIDE OF A SUPPORT, A THERMOSENSITIVE ELEMENT AND AN OUTERMOST LAYER OF A CURED POLYMER, ACIDIFIED COLLOIDAL SILICA, AND A BUFFER OF AN ACID AND A NONMETALLIC SALT OF AN ACID AGFA-GEVAERT (BE) 2000-10-03 US disclosed
US-6051530-A RECORDING AN IMAGES; MULTILAYER AGFA-GEVAERT (BE) 2000-04-18 US disclosed
EP-0924098-A1 Outermost layers for use in thermographic recording materials AGFA-GEVAERT N.V. (BE) 1999-06-23 EP disclosed
EP-0924097-A1 Outermost layers for use in thermographic recording material AGFA-GEVAERT N.V. (BE) 1999-06-23 EP disclosed