SCHEMBL7167329

SCHEMBL7167329

CCCCCCCCCCCCCCC(NC(=O)CCCCCCCCCCC(CCCCCC)NCC(=O)c1cc2ccc(N(CC)CC)cc2oc1=O)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.50
▸ HPGD P15428 3/20 0.50
▸ SMN1; SMN2 Q16637 3/20 0.50
▸ KDM4E B2RXH2 3/20 0.50
▸ HSD17B10 Q99714 2/20 0.50
▸ SLC16A3 O15427 1/20 0.50
▸ ALOX15 P16050 1/20 0.50
▸ SLC16A1 P53985 1/20 0.50
▸ MEN1 O00255 6/20 0.48
▸ MAPT P10636 6/20 0.48
▸ KMT2A Q03164 6/20 0.48
▸ ATM Q13315 3/20 0.48
▸ MAOB P27338 3/20 0.48
▸ USP2 O75604 2/20 0.48
▸ CYP1A2 P05177 1/20 0.48
▸ CYP2C19 P33261 1/20 0.48
▸ LMNA P02545 1/20 0.47
▸ TP53 P04637 1/20 0.47
▸ CASP1 P29466 1/20 0.47
▸ CASP7 P55210 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8707677 0.90 ALDH1A1 (0.55) ALDH1A1HPGDSMN1; SMN2KDM4EHSD17B10
SCHEMBL30158125 0.90 ALDH1A1 (0.55) ALDH1A1HPGDSMN1; SMN2KDM4EHSD17B10
SCHEMBL8562232 0.85 ALDH1A1 (0.52) ALDH1A1HPGDSMN1; SMN2KDM4EHSD17B10
SCHEMBL16573482 0.84 ALDH1A1 (0.52) ALDH1A1HPGDSMN1; SMN2KDM4EHSD17B10
SCHEMBL7029313 0.83 MEN1 (0.49) ALDH1A1HPGDSMN1; SMN2KDM4EHSD17B10
SCHEMBL16573485 0.76 MEN1 (0.48) ALDH1A1HPGDSMN1; SMN2KDM4EHSD17B10
SCHEMBL21615668 0.74 KMT2A (0.60) ALDH1A1HPGDSMN1; SMN2KDM4EHSD17B10
SCHEMBL411971 0.73 ALDH1A1 (0.57) ALDH1A1HPGDSMN1; SMN2KDM4EHSD17B10
SCHEMBL12651748 0.73 MEN1 (0.74) ALDH1A1HPGDSMN1; SMN2KDM4EHSD17B10
SCHEMBL8592677 0.72 ALDH1A1 (0.77) ALDH1A1HPGDSMN1; SMN2KDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0802788-A4 NOVEL THERAPEUTIC DELIVERY SYSTEMS UNGER EVAN C (US) 1998-09-09 — — EP claimed
EP-0712293-A4 METHODS OF PREPARING GAS AND GASEOUS PRECURSOR-FILLED MICROSPHERES UNGER EVAN C (US) 1998-05-06 — — EP claimed
EP-0802788-A1 NOVEL THERAPEUTIC DELIVERY SYSTEMS UNGER, Evan C (US) 1997-10-29 — — EP claimed
EP-0712293-A1 METHODS OF PREPARING GAS AND GASEOUS PRECURSOR-FILLED MICROSPHERES UNGER, Evan C (US) 1996-05-22 — — EP claimed
WO-1994028780-A2 METHODS OF PREPARING GAS AND GASEOUS PRECURSOR-FILLED MICROSPHERES UNGER EVAN C (US) 1994-12-22 — — WO claimed
WO-1994028874-A1 NOVEL THERAPEUTIC DELIVERY SYSTEMS UNGER EVAN C (US) 1994-12-22 — — WO claimed
US-20250195621-A1 SYNTHETIC PLATELETS UNIV CASE WESTERN RESERVE (US) 2025-06-19 — — US disclosed
US-20190247526-A1 Microbubble Compositions, Method of Making Same, and Method Using Same Microvascular Therapeutics LLC 2019-08-15 — — US disclosed
US-10279053-B2 Microbubble compositions, method of making same, and method using same NUVOX PHARMA LLC (US) 2019-05-07 — — US disclosed
WO-2013013067-A2 MICROBUBBLE COMPOSITIONS, METHOD OF MAKING SAME, AND METHOD USING SAME NUVOX PHARMA, L.L.C. (US) 2013-01-24 — — WO disclosed
US-20130022550-A1 Microbubble Compositions, Method of Making Same, and Method Using Same Microvascular Therapeutics LLC 2013-01-24 — — US disclosed
WO-2012142362-A2 SYNTHETIC PLATELETS CASE WESTERN RESERVE UNIVERSITY (US) 2012-10-18 — — WO disclosed
EP-1337278-A2 SIMULTANEOUS IMAGING OF CARDIAC PERFUSION AND A VITRONECTIN RECEPTOR TARGETED IMAGING AGENT Bristol-Myers Squibb Medical Imaging, Inc. (US) 2003-08-27 — — EP disclosed
US-6548047-B1 Using lecithin, cephalin filled with gases; scanning; medical diagnosis BRISTOL-MYERS SQUIBB MEDICAL IMAGING, INC. 2003-04-15 — — US disclosed
WO-2002055111-A2 SIMULTANEOUS IMAGING OF CARDIAC PERFUSION AND A VITRONECTIN RECEPTOR TARGETED IMAGING AGENT BRISTOL MYERS SQUIBB MEDICAL I (US) 2002-07-18 — — WO disclosed
US-5830430-A Cationic lipids and the use thereof IMARX PHARMACEUTICAL CORP. (US) 1998-11-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130022550-A1 Microbubble Compositions, Method of Making Same, and Method Using Same SHH, GLI1, SON ALDH1A1 3850/4885HPGD 4283/4885SMN1; SMN2 2109/4885
US-20190247526-A1 Microbubble Compositions, Method of Making Same, and Method Using Same SHH, GLI1, SON ALDH1A1 3850/4885HPGD 4283/4885SMN1; SMN2 2109/4885
US-10279053-B2 Microbubble compositions, method of making same, and method using same SHH, GLI1, SON ALDH1A1 3850/4885HPGD 4283/4885SMN1; SMN2 2109/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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