SCHEMBL7167347

SCHEMBL7167347

CC(C)(C)c1ccc(-c2ncc(-c3ccc(-c4ccccc4)cc3)o2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.72
TSHR P16473 1/20 0.72
CASP1 P29466 1/20 0.72
RAB9A P51151 7/20 0.62
KMT2A Q03164 4/20 0.62
MEN1 O00255 3/20 0.62
MITF O75030 1/20 0.62
PTPN1 P18031 5/20 0.55
PTPN2 P17706 2/20 0.55
NPC1 O15118 6/20 0.55
KDM4E B2RXH2 5/20 0.55
ALDH1A1 P00352 5/20 0.55
HPGD P15428 5/20 0.55
HSD17B10 Q99714 4/20 0.55
TP53 P04637 4/20 0.55
SMN1; SMN2 Q16637 4/20 0.55
GAA P10253 4/20 0.55
LMNA P02545 1/20 0.55
CYP1A2 P05177 1/20 0.55
GLA P06280 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7160732 1.00 ALOX15 (0.72) ALOX15TSHRCASP1RAB9AKMT2A
SCHEMBL4874341 0.98 ALOX15 (0.74) ALOX15TSHRCASP1RAB9AKMT2A
SCHEMBL29084731 0.98 ALOX15 (0.74) ALOX15TSHRCASP1RAB9AKMT2A
SCHEMBL29083928 0.88 ALOX15 (0.57) ALOX15TSHRCASP1RAB9AKMT2A
SCHEMBL14278930 0.87 ALOX15 (0.77) ALOX15TSHRCASP1RAB9AKMT2A
SCHEMBL12776806 0.87 ALOX15 (0.54) ALOX15TSHRCASP1RAB9AKMT2A
SCHEMBL1267325 0.87 ALOX15 (0.96) ALOX15TSHRCASP1RAB9AKMT2A
SCHEMBL2684521 0.87 ALOX15 (0.96) ALOX15TSHRCASP1RAB9AKMT2A
SCHEMBL77084 0.87 ALOX15 (0.96) ALOX15TSHRCASP1RAB9AKMT2A
SCHEMBL9238093 0.87 ALOX15 (0.96) ALOX15TSHRCASP1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6566807-B1 Having lowered resistances of organic layers, having a high light emitting efficiency, and being excellent in electrooptical characteristics SHARP KABUSHIKI KAISHA (JP) 2003-05-20 US disclosed
US-6525465-B1 Cesium-, rubidium-, or potassium bromide or iodide SHARP KABUSHIKI KAISHA (JP) 2003-02-25 US disclosed
EP-1017118-A2 Organic electroluminescent element and production method thereof Sharp Kabushiki Kaisha (JP) 2000-07-05 EP disclosed