Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 5/20 | 0.44 |
| ▸ | BMP1 | P13497 | 3/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | NPY4R | P50391 | 5/20 | 0.37 |
| ▸ | NPY1R | P25929 | 4/20 | 0.37 |
| ▸ | NPY2R | P49146 | 3/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7171599 | 0.87 | AVPR1B (0.42) | AVPR1BBMP1AVPR1APLGNPY4R | |
| SCHEMBL7171393 | 0.85 | AVPR1B (0.46) | AVPR1BBMP1AVPR1APLGNPY4R | |
| SCHEMBL9329697 | 0.81 | AVPR1B (0.52) | AVPR1BBMP1AVPR1APLG | |
| SCHEMBL1509780 | 0.81 | AVPR1B (0.54) | AVPR1BBMP1AVPR1APLG | |
| SCHEMBL30007346 | 0.81 | AVPR1B (0.54) | AVPR1BBMP1AVPR1APLG | |
| SCHEMBL7898282 | 0.81 | AVPR1B (0.54) | AVPR1BBMP1AVPR1APLG | |
| SCHEMBL1509781 | 0.81 | AVPR1B (0.54) | AVPR1BBMP1AVPR1APLG | |
| SCHEMBL7368157 | 0.78 | AVPR1B (0.47) | AVPR1BBMP1AVPR1APLG | |
| SCHEMBL2873083 | 0.77 | AVPR1B (0.48) | AVPR1BBMP1AVPR1APLG | |
| SCHEMBL29816989 | 0.77 | AVPR1B (0.48) | AVPR1BBMP1AVPR1APLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789578-B1 | MULTICATALYTIC PROTEASE INHIBITORS | CEPHALON INC (US) | 2003-06-04 | — | — | EP | disclosed |
| EP-0789578-A4 | MULTICATALYTIC PROTEASE INHIBITORS | CEPHALON INC (US) | 2000-09-20 | — | — | EP | disclosed |
| US-5990083-A | Multicatalytic protease inhibitors | CEPHALON, INC. (US) | 1999-11-23 | — | — | US | disclosed |
| US-5830870-A | PREVENT LOSS OF MUSCLE MASS | CEPHALON, INC. (US) | 1998-11-03 | — | — | US | disclosed |
| EP-0789578-A1 | MULTICATALYTIC PROTEASE INHIBITORS | CEPHALON, INC. (US) | 1997-08-20 | — | — | EP | disclosed |
| US-5614649-A | TREATMENT OF MUSCULAR DISORDERS, SUBSTITUTED GUANIDINES | CEPHALON, INC. (US) | 1997-03-25 | — | — | US | disclosed |
| WO-1996014857-A1 | MULTICATALYTIC PROTEASE INHIBITORS | CEPHALON, INC. (US) | 1996-05-23 | — | — | WO | disclosed |