Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SGK1 | O00141 | 1/20 | 0.37 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6705270 | 0.94 | PREP (0.44) | PREPPDK2ABL1NOTUMCA12 | |
| SCHEMBL6058804 | 0.85 | PREP (0.46) | PREPCA12CA1CA9 | |
| SCHEMBL6697474 | 0.74 | HTR1D (0.39) | PREPPDK2NOTUMALDH1A1 | |
| SCHEMBL6698482 | 0.73 | ABL1 (0.43) | PDK2EGFRABL1SMN1; SMN2GABRA5 | |
| SCHEMBL6701789 | 0.73 | HPGD (0.47) | PREPABL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8906116 | 0.73 | CA1 (0.56) | PREPNOTUMCA12CA1CA2 | |
| SCHEMBL16171288 | 0.73 | PREP (0.51) | PREPSMN1; SMN2CA12CA1CA2 | |
| SCHEMBL6058993 | 0.72 | PREP (0.41) | PREPCA12CA1CA9 | |
| SCHEMBL6860354 | 0.72 | ABL1 (0.42) | PREPPDK2EGFRABL1SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL6697477 | 0.71 | ABL1 (0.41) | PREPPDK2EGFRABL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6563008-B2 | Treatment of disorders linked to hypofolliculinemia and of certain estrogen-dependent pathologies such as prostatic adenomas or carcinomas, and of benign tumours of the breast | AVENTIS PHARMA S.A. (FR) | 2003-05-13 | — | — | US | disclosed |