Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | CA9 | Q16790 | 4/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TPMT | P51580 | 3/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6705270 | 0.88 | PREP (0.44) | PREPCA12CA1CA9 | |
| Biphenyl SCHEMBL7167410 | 0.85 | PREP (0.40) | PREPCA12CA1CA9 | |
| SCHEMBL6058993 | 0.79 | PREP (0.41) | PREPCA12CA1CA9THRA | |
| SCHEMBL6058502 | 0.77 | PREP (0.45) | PREPTPMT | |
| SCHEMBL6542930 | 0.76 | CA1 (0.52) | PREPCA12CA1CA9NR4A2 | |
| SCHEMBL6155680 | 0.73 | PLA2G2A (0.41) | PREPCA12CA1CA9TPMT | |
| SCHEMBL3296656 | 0.73 | CA12 (0.41) | PREPCA12CA1CA9TPMT | |
| SCHEMBL6654531 | 0.70 | TPMT (0.48) | PREPCA12CA1CA9TPMT | |
| SCHEMBL29053391 | 0.70 | CA12 (0.46) | PREPCA12CA1CA9 | |
| SCHEMBL23491348 | 0.69 | PREP (0.57) | PREPCA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877607-B1 | BIPHENYL COMPOUNDS AND USE THEREOF AS OESTROGENIC AGENTS | AVENTIS PHARMA SA (FR) | 2006-11-15 | — | — | EP | disclosed |